Tae-Sik Kim

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Although the graft-versus-tumor (GVT) effect of donor-derived T cells after allogeneic hematopoietic stem cell transplantation has been used as an effective adoptive immunotherapy, the antitumor effects of cord blood (CB) transplantation have not been well studied. We established the animal model by transplantation of CB mononuclear cells and/or tumor cells(More)
PURPOSE While the inflammatory cytokine interleukin-18 (IL-18) is known to activate natural killer (NK) cells, its precise role in cancer is controversial. In this study, we investigated the role of tumor-derived IL-18 on peripheral blood NK cells in breast cancer patients. RESULTS In breast cancer cell lines, IL-18 was expressed and secreted in the(More)
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