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A feb-batch operation for the production of bovine somatotropin (bST) under the control of tryptophan promoter in Escherichia coli was investigated. The plasmid used contains a two-cistron system and altered codon usage for higher expression of bST. Specific growth rate is an important parameter in the fermentation, because it affects the production of(More)
To facilitate future decisions regarding the usefulness of rotavirus vaccines in the Republic of Korea, active surveillance was conducted in a network of clinics, emergency departments, and hospitals serving Jeongeub District, Korea. Children with diarrhea underwent standard clinical evaluations, and stool specimens were collected to test for the presence(More)
Dear Sir, I read with great interest the recent article by Grippaudo et al. [1]. The authors evaluated the role of WBC scintigraphy in the diagnosis and follow-up of patients with suspected soft tissue infection caused by dermal fillers in the face. They concluded that scintigraphy with radiolabelled WBC was found to be the most accurate method for(More)
The physiopathogenesis of keloid scars is not well understood. This report aims to present the authors’ experiences with facial keloids, to evaluate their treatment outcomes via a prospective study, and to identify risk factors involved in facial keloid recurrence. Patients with facial keloids were treated with surgical excision followed by intra- and(More)
Tacrine (THA; 1,2,3,4-tetrahydro-9-aminoacridine) is an anticholinesterase agent which has been used clinically, most recently in the treatment of Alzheimer-type dementias. This paper describes the methodology for the isolation and quantitation of THA at therapeutic levels in serum from human subjects. Using C18 Bond Elut columns and an HPLC/fluorometry(More)
BACKGROUND A previous study described the outcomes of a treatment protocol using a prospective design and identified three clinical risk factors for recurrent keloids. OBJECTIVE To introduce a novel classification of earlobe keloids through a retrospective study and describe the appropriate surgical methods according to this new classification. METHODS(More)
Keloid formation is one of the most challenging clinical problems in wound healing. With increasing frequency of open heart surgery, chest keloid formations are not infrequent in the clinical practice. The numerous treatment methods including surgical excision, intralesional steroid injection, radiation therapy, laser therapy, silicone gel sheeting, and(More)
Recently, rhinoplasty techniques have advanced significantly and are frequently combined with columellar struts using conchal cartilage grafts to sufficiently reshape the nasal tip. For this reason, auricular keloids following harvesting of conchal cartilage grafts are expected to occur with greater frequency. The aim of this study was to share our(More)
Polymethylmethacrylate (PMMA) filler is widely used for the correction of wrinkles because of its relative long-lasting cosmetic improvements and the rarity of reported complications. However, early and delayed complications, ranging from minor to severe, can occur following PMMA filler injection. We evaluated and treated 13 cases of PMMA filler-related(More)