Tadeusz Parnowski

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In 64 individuals with dementia (26 Alzheimer type, 34 of vascular origin and 4 other types of dementia) apolipoprotein E genotype was identified. Frequency of epsilon4 allele was 36.5% in Alzheimer patients and 32.4% in vascular dementia ones. In a group of 39 nondemented individuals of the same age the epsilon4 frequency was 11.5%. In demented patients,(More)
AIM The aim of the study was to assess efficacy and safety of electroconvulsive therapy. METHODS 43 patients included into the study were hospitalised in The Institute of Psychiatry and Neurology and received all together over 400 bilateral electroconvulsive procedures. Most of the patients (N = 25) were qualified for electroconvulsive therapy due to(More)
Data was collected from a group of 100 randomly selected subjects from a city population above the age of 65 years. The aim of the research was to prove the reliability and validity of the research tools: the Folstein's MMSE and the Blessed's IMC. Thirty subjects were eliminated from the sample the remaining 70 were grouped according to gender for further(More)
BACKGROUND We analyzed metabolic profile of patients with cognitive dysfunctions by means of levels of lipoproteins, glycaemia and hypertension. RESEARCH DESIGN AND METHODS In naturalistic, open manner, we studied 100 persons--44 without cognitive dysfunctions, 17 with MCI and 39 with dementia. Patients were grouped according to ICD-10, NIA/AA, McKhann's(More)
Mild to moderate dementia fulfilling ICD-10 criteria and with MMSE score below 24 was analyzed in a sample of 46 randomly chosen elderly people. Selected scales derived from Polish version of CAMDEX and its cognitive section (CAMCOG) were used for assessment of clinical picture. Psychopathological symptoms, e.g., depression were frequent, especially in(More)
BACKGROUND Long-term safety and efficacy of Exelon (rivastigmine) was evaluated in a multi-center open-label study of 62 patients with probable mild to moderate Alzheimer's disease living in community setting. MATERIAL/METHODS The patients started treatment with 1.5 mg bid (3 mg/day) Exelon and were scheduled to receive doses of 1.5 mg bid Exelon(More)
The aim of the study was to summarize the efficacy and tolerability of paliperidone palmitate, an atypical long-acting antipsychotic drug. Paliperidone is a 9-hydroxy metabolite of risperidone with a slightly different receptor profile and significantly different pharmacokinetic profile. After the short review of its pharmacological properties, the efficacy(More)