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Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-kappaB for Toll-like receptor- and NOD-dependent activation.
The Distribution of Transient Receptor Potential Melastatin-8 in the Rat Soft Palate, Epiglottis, and Pharynx
- Tadasu Sato, Masatoshi Fujita, H. Ichikawa
- Biology, MedicineCellular and Molecular Neurobiology
- 1 March 2013
The present study suggests that TRPM8 can respond to cold stimulation when food and drinks pass through oral and pharyngeal cavities.
PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2
- A. Uehara, Tadasu Sato, Atsushi Iwashiro, S. Yokota
- Medicine, BiologyDiagnostic pathology
- 14 July 2009
PR3-ANCA prime human mononuclear cells to produce cytokines upon stimulation with various microbial components by up-regulating the TLR and NOD signaling pathway, and these mechanisms may partially participate in the inflammatory process in Wegener's granulomatosis.
Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function
- Scott D. Ryan, Andrew R. Ferrier, R. Kothary
- Psychology, BiologyMolecular biology of the cell
- 15 February 2012
Sensory neurodegeneration results primarily from the loss of the dystonin-a2 isoform, which is attributed a novel role in maintenance of organelle integrity.
Transgenic expression of neuronal dystonin isoform 2 partially rescues the disease phenotype of the dystonia musculorum mouse model of hereditary sensory autonomic neuropathy VI.
Restoring dystonin-a2 expression in the nervous system, particularly within sensory neurons, prevented the disorganization of organelle membranes and microtubule networks, attenuated the degeneration of sensory neuron subtypes and ameliorated the phenotype and increased life span in these mice.
Transient receptor potential melastatin-3 in the rat sensory ganglia of the trigeminal, glossopharyngeal and vagus nerves
Motor Unit Abnormalities in Dystonia musculorum Mice
- Y. De Repentigny, Andrew R. Ferrier, Scott D. Ryan, Tadasu Sato, R. Kothary
- Biology, PsychologyPloS one
- 15 June 2011
Neuromuscular defects that likely contribute to the dt27J pathology are revealed and a critical role for dystonin outside of sensory neurons is identified and identified.
Distribution of TRPV1 and TRPV2 in the human stellate ganglion and spinal cord
Promotion of arthritis and allergy in mice by aminoglycoglycerophospholipid, a membrane antigen specific to Mycoplasma fermentans.
Glycoglycerophospholipid alone exhibited little inflammatory effect, but promoted both collagen-induced arthritis and nickel (Ni) allergy, although less powerfully than Escherichia coli lipopolysaccharide.
Role of cytokines in lavage or drainage fluid after hemithyroidectomy in wound healing: Involvement of histamine in the acceleration and delay of wound healing
- M. Arai, H. Ogita-Nakanishi, R. Yoshida
- Medicine, BiologyWound repair and regeneration : official…
- 1 March 2012
High (or low) levels of histamine in the postoperative lavage fluids with low (or high) levels in the drainage fluids on POD1 caused earlier (or the delay of) wound healing, suggesting involvement of histamines in the acceleration and delay of wound healing.