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  • Tsuyoshi Minematsu, Tadashi Hashimoto, Toshiko Aoki, Takashi Usui, Hidetaka Kamimura
  • Medicine, Chemistry
  • Drug Metabolism and Disposition
  • 2008 (First Publication: 1 August 2008)
  • Zonampanel monohydrate ([2,3-dioxo-7-(1H-imidazol-1-yl)-6-nitro-1,2,3,4-tetrahydro-1-quinoxalinyl] acetic acid monohydrate, YM872) is a novel α-amino-3-hydroxy-5-methylisoxazole-4-propionic acidExpand
  • Tadashi Hashimoto, Shinichi Narikawa, +4 authors Hitoshi Endou
  • Chemistry, Medicine
  • Drug metabolism and disposition: the biological…
  • 2004 (First Publication: 1 October 2004)
  • Zonampanel monohydrate (YM872; [2,3-dioxo-7-(1H-imidazol-1-yl)-6-nitro-1,2,3,4-tetrahydro-1-quinoxalinyl]acetic acid monohydrate) is a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acidExpand
  • Toshifumi Shiraga, Kanako Yajima, +5 authors Takashi Usui
  • Chemistry, Medicine
  • Drug Metabolism and Disposition
  • 2012 (First Publication: 1 February 2012)
  • Darexaban maleate is a novel oral direct factor Xa inhibitor, which is under development for the prevention of venous thromboembolism. Darexaban glucuronide was the major component in plasma afterExpand
  • Tadashi Hashimoto, Katsuhiro Suzuki, +8 authors Takashi Usui
  • Chemistry, Medicine
  • Xenobiotica; the fate of foreign compounds in…
  • 2013 (First Publication: 2 May 2013)
  • 1. The absorption, metabolism and excretion of darexaban (YM150), a novel oral direct factor Xa inhibitor, were investigated after a single oral administration of [14C]darexaban maleate at a dose ofExpand
  • Tsuyoshi Minematsu, Laurie Felder, +5 authors Hidetaka Kamimura
  • Medicine, Chemistry
  • Biomedical chromatography : BMC
  • 2008 (First Publication: 1 July 2008)
  • This paper describes a sensitive and selective liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for determination of the novel survivin suppressant YM155,Expand