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Effects of pectin on fatty acid and glucose absorption and on thickness of unstirred water layer in rat and human intestine
Effects of pectin, a soluble dietary fiber, on fatty acid and glucose absorption were studied in vivoin rats and humans by perfusing the intestine with linoleic acid and glucose solutions with and… Expand
Effect of peptide chain length on absorption and intact transport of hydrolyzed soybean peptide in rat intestinal everted sac
In this study using everted sacs of rat jejunum, we investigated the difference in absorption of two types of soybean peptides (small peptide: SP, and large peptide: LP). We investigated the… Expand
Potentiation of slow component of delayed rectifier K+ currentby cGMP via two distinct mechanisms: inhibition of phosphodiesterase 3 and activation of protein kinase G
- K. Shimizu, Yutaka Shintani, W. Ding, H. Matsuura, Tadao Bamba
- Chemistry, Medicine
- British journal of pharmacology
- 1 September 2002
Regulation of the slowly activating component of delayed rectifier K+ current (IKs) by intracellular guanosine 3′5′ cyclic monophosphate (cGMP) was investigated in guinea‐pig sino‐atrial (SA) node… Expand
Activation of transepithelial ion transport by secretin in human intestinal Caco-2 cells.
- M. Fukuda, A. Ohara, Tadao Bamba, Y. Saek
- Chemistry, Medicine
- The Japanese journal of physiology
- 1 April 2000
Secretin stimulates bicarbonate secretion from pancreatic duct cells, but what influence secretin exerts on intestinal tissues remains to be clarified. The aim of this study is to examine effects of… Expand
Effect of fasting and feeding on polyamines and related enzymes along the villus: crypt axis.
Fasting and feeding have profound effects on crypt cell production and small bowel mucosal growth but the mechanism whereby food stimulates villus tip enterocytes to influence crypt cell production… Expand
Rapid intestinal ischaemia‐reperfusion injury is suppressed in genetically mast cell‐deficient Ws/Ws rats
Ws/Ws rats have a small deletion of the c‐kit gene, and are deficient in both mucosal and connective tissue‐type mast cells. In this study, the role of mucosal type mast cells (MMC) in the… Expand
The role of mucosal mast cell degranulation and free-radical generation in intestinal ischaemia-reperfusion injury in rats.
- T. Kimura, Y. Fujiyama, +4 authors Tadao Bamba
- European journal of gastroenterology & hepatology
- 1 August 1998
OBJECTIVES In this study, we determined the role of mucosal mast cell (MMC) activation in the pathogenesis of intestinal ischaemia-reperfusion (I/R) injury by immunohistochemical analysis using… Expand
Hepatoprotective effect of a curcumin/absinthium compound in experimental severe liver injury
OBJECTIVE: A preliminary in vitro study with hepatocyte culture showed that concentrations as low as 10 µg/mL of PN-M001 are able to significantly mitigate CCl4 hepatocyte damage (P < 0.05)… Expand
Monitor Peptide (Rat Pancreatic Secretory Trypsin Inhibitor) Directly Stimulates the Proliferation of the Nontransformed Intestinal Epithelial Cell Line, IEC-6
- M. Fukuda, Y. Fujiyama, M. Sasaki, A. Andoh, Tadao Bamba, T. Fushiki
- Biology, Medicine
- 1 July 1998
Background/Aims: The growth-stimulating activity of monitor peptide [rat pancreatic secretory trypsin inhibitor (PSTI)-61] was evaluated in the rat intestinal epithelial cell line IEC-6. In response… Expand
Nutritional management of Crohn's disease with a peptide-based enteral formula.
- S. Hosoda, T. Shimoyama, +4 authors N. Hiwatashi
- Asia Pacific journal of clinical nutrition
- 1 June 1993
We examined a nutritional approach to the therapy of Crohn's disease with an enteral formula ('Enterued', Terumo Corporation, Tokyo, Japan) which contains low molecular weight peptides as a protein… Expand