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Studies towards the synthesis of the hypermodified nucleoside of rat liver phenylalanine transfer ribonucleic acid: improved synthesis of the base beta-hydroxywybutine.
  • T. Itaya, T. Kanai
  • Medicine, Chemistry
  • Chemical & pharmaceutical bulletin
  • 15 August 1998
An improved synthesis of the key intermediates (3 and 8) for the synthesis of beta-hydroxywybutines [[R-(R*,S*)]- and [S-(R*,R*)]-4], the most probable structures for the minor base from rat liverExpand
  • 7
Synthesis of 2-Aminomethyl-5-tert-butylphenols
Mannich-type aminomethylation of m-ten-butylphenol (1) with a variety of secondary amines and formalin was carried out in ethanol at 70-80°C for 2 h. The reaction with amines such as pyrrolidine,Expand