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DNA gyrase inhibitors: Progress and synthesis of potent compounds as antibacterial agents.
DNA gyrase is classified as topoisomerase II, an ATP-dependent enzyme that is vital in the transcription, replication of DNA and chromosome segregation processes. It plays a crucial role in allExpand
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Polysaccharides as potential anticancer agents-A review of their progress.
Cancer is one of the most common diseases seen in developed countries, with over 1.6 million new cases estimated in 2017, in the US alone. The current chemotherapeutic drugs available for theExpand
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Recent advances in delivery of antifungal agents for therapeutic management of candidiasis.
Candidiasis is a fungal infection caused by yeasts that belong to the genus Candida. There are over twenty species of Candida yeasts that can cause infection in humans, the most common of which isExpand
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PhytoNanotechnology: Enhancing Delivery of Plant Based Anti-cancer Drugs
Natural resources continue to be an invaluable source of new, novel chemical entities of therapeutic utility due to the vast structural diversity observed in them. The quest for new and better drugsExpand
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Bone Health and Natural Products- An Insight
Bone metabolism involves a complex balance between matrix deposition, mineralization, and resorption. Numerous evidences have revealed that dietary components and phytoconstituents can influenceExpand
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Phytochemicals and PI3K Inhibitors in Cancer—An Insight
In today's world of modern medicine and novel therapies, cancer still remains to be one of the prime contributor to the death of people worldwide. The modern therapies improve condition of cancerExpand
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Selective drug deposition in lungs through pulmonary drug delivery system for effective management of drug-resistant TB
ABSTRACT Introduction: The emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) is a major health issue and continues to be a global healthExpand
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Immunological Studies on the Aerial Roots of the Indian Banyan
The aqueous extract of the aerial roots the Indian Banyan, Ficus benghalensis L. (Family: Moraceae) was evaluated for its effect on both specific and non-specific immunity. This extract exhibited aExpand
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Design and Development of Novel 2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as Selective COX-II Inhibitor
Background: A novel series of 2-(Morpholin-4-yl)-N-phenylquinazolin-4-amine derivatives were synthesized and confirmed with spectral and elemental techniques. Methods: The compounds were tested forExpand
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Targeting tumor microenvironment to curb chemoresistance via novel drug delivery strategies
ABSTRACT Introduction: Tumor is a heterogeneous mass of malignant cells co-existing with non-malignant cells. This co-existence evolves from the initial developmental stages of the tumor and is oneExpand
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