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1. The pharmacokinetics and pharmacodynamics of intranasal (IN) and oral 1-deamino-8-D-arginine vasopressin (DDAVP) were compared in 10 Chinese adults with central diabetes insipidus previously controlled on IN DDAVP. This was followed by comparison of the acute pharmacodynamics of commonly used oral preparations (containing 100, 200 and 400 micrograms per(More)
In this retrospective study, the prevalence of chronic microangiopathic complications was determined in 474 Chinese patients with non-insulin dependent diabetes mellitus (NIDDM) who presented within 1 year of diagnosis to the diabetes clinic from January 1990 to December 1996. Mean age (+/- S.E.) was 53.6 (+/- 0.6) years. The overall prevalence of(More)
Osteoporosis has become an important health problem in postmenopausal Asian populations as the prevalence of hip and vertebral fractures in some Asian countries has risen to approach that of Caucasian populations. Risedronate, a pyridinyl-bisphosphonate agent, is a potent inhibitor of bone resorption. Risedronate increases bone mineral density (BMD),(More)
Key Messages 1. Type 2 diabetic patients with chronic kidney disease receiving structured care (SC) by a diabetologist-nurse team or usual care (UC) had a similar incidence of end-stage renal disease (24 of 104 vs 24 of 101) after intervention for 2 years. 2. Patients receiving SC were three times more likely to attain three or more predefined treatment(More)
OBJECTIVE To determine the efficacy of acarbose, compared with placebo, on the metabolic control of NIDDM patients inadequately controlled on maximal doses of conventional oral agents. RESEARCH DESIGN AND METHODS In this three-center double-blind study, 90 Chinese NIDDM patients with persistent poor glycemic control despite maximal doses of sulfonylurea(More)
This article reviews the available data on the study of iodine deficiency disorders in Hong Kong and to discuss the approach towards preventing such disorders in Hong Kong. The importance of iodine and iodine deficiency disorders is described, and the available data on the dietary iodine intake and urinary iodine concentration in different populations of(More)
Department of Medicine, The University of Hong Kong , Department of Medicine, Queen Elizabeth Hospital, Department of Orthopaedic Surgery, Queen Mary Hospital, Department of Rehabilitation, Kowloon Hospital, Department of Orthopaedics & Traumatology, Tuen Mun Hospital, Department of Family Medicine, HK E&W Cluster, Department of Nuclear Medicine, Pamela(More)
Accepted 7 February 1996 A 38-year-old man presenting with progressive blurring of vision was diagnosed to have a pituitary macroadenoma with suprasellar extension. He underwent left frontal craniotomy with subtotal excision of the tumour without a proper pre-operative endocrine work up. He was put on prophylactic anticonvulsant (sodium valproate) after the(More)
A 19 year old female patient with typical features of acromegaly was found to have an extensive pituitary tumour with suprasellar, lateral and inferior extensions. Magnetic resonance imaging (MRI) also showed a portion of the tumour extending from the right cavernous sinus through the foramen ovale to become extracranial. Serum growth hormone (GH) was 52.6(More)
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