TJM Smeets

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In normal and dwarfed Snell mice, the postnatal development through the first 70 days of life of the proximal tibial epiphysis and its growth plate has been studied, using histometric techniques and qualitative histological descriptions. The tibia appears to be fairly representative for longitudinal skeletal growth, since a linear relationship between(More)
In Snell dwarf mice, the influence of short-term treatment with human growth hormone (hGH) or thyroxine on the proliferative and sulphation activity of the proximal tibial growth plate was studied. By autoradiographic methods, the [3H]methylthymidine incorporation after a single injection was measured, after 2 hr incorporation time. The labelling index was(More)
The separation of tylosin by micellar electrokinetic capillary chromatography with a mixed micelle system is described. Good selectivity was obtained with sodium phosphate buffer (80 mM, pH 7.5) containing 20 mM sodium cholate and 7 mM cetyltrimethylammonium bromide (CTAB). This method permits tylosin to be separated from its closely related substances(More)