TJ Gibson

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Objective Understanding the molecular and cellular mechanisms of ciliopathies is vital for dissecting their pathogenesis, identifying appropriate therapeutic targets and designing effective treatments. Recent advances in DNA sequen-cing technology have provided a torrent of genetic data that can now be used to elucidate the genetic basis of human diseases.(More)
SYSCILIA, " A systems biology approach to dissect cilia function and its disruption in human genetic disease " Primary cilia are basically signaling hubs, harboring amongst others the noncanonical WNT, Hedgehog,and PDGF signaling systems, and their disruption leads to striking developmental defects. Some ciliopathy-associated proteins have recently been(More)
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