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A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y.
Thousands die each year from sudden infant death syndrome (SIDS). Neither the cause nor basis for varied prevalence in different populations is understood. While 2 cases have been associated withExpand
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Regulation of Glucagon Secretion in Normal and Diabetic Human Islets by γ-Hydroxybutyrate and Glycine*
Background: β-Cells regulate α-cells via paracrine mechanisms. Results: A GABA shunt defect impairs glucose suppression of glucagon secretion in diabetic human islets. Glucagon secretion is inhibitedExpand
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A novel monopartite dsRNA virus isolated from the phytopathogenic fungus Ustilaginoidea virens and ancestrally related to a mitochondria-associated dsRNA in the green alga Bryopsis.
In this study, we describe a novel mycovirus isolated from Ustilaginoidea virens, which was designated Ustilaginoidea virens nonsegmented virus 1 (UvNV-1). The sequence analysis revealed that UvNV-1Expand
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Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions
Ig heavy chain (IgH) class-switch recombination (CSR) replaces the IgH Cμ constant region exons with one of several sets of downstream IgH constant region exons (e.g., Cγ, Cε, or Cα), which affectsExpand
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Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry
  • L. Zhu, Z. Hu, +8 authors R. Zenobi
  • Medicine, Chemistry
  • Analytical and bioanalytical chemistry
  • 20 July 2010
AbstractBy gently bubbling nitrogen gas through beer, an effervescent beverage, both volatile and non-volatile compounds can be simultaneously sampled in the form of aerosol. This allows for fastExpand
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GSK3β-Dzip1-Rab8 Cascade Regulates Ciliogenesis after Mitosis
The primary cilium, which disassembles before mitotic entry and reassembles after mitosis, organizes many signal transduction pathways that are crucial for cell life and individual development.Expand
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A Simple and Efficient Method for Assembling TALE Protein Based on Plasmid Library
DNA binding domain of the transcription activator-like effectors (TALEs) from Xanthomonas sp. consists of tandem repeats that can be rearranged according to a simple cipher to target new DNAExpand
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Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases
Prior to the development of zinc-finger nuclease technology, genetic manipulation by gene targeting achieved limited success in mammals, with the exception of mice and rat. Although ZFNs demonstratedExpand
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Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China
Abstract In this study, 418 IBVs were isolated in samples from 1717 chicken flocks. Twenty-nine of the isolates were classified as the Massachusetts genotype. These 29 isolates, as well as twoExpand
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Early Cretaceous exhumation of the Sulu orogenic belt as a consequence of the eastern Eurasian tectonic extension: insights from the newly discovered Wulian metamorphic core complex, eastern China
The mechanisms of thinning of the lithosphere and destruction of the North China Craton have been debated in recent decades. Their causal link with regional tectonic extension is well exemplified byExpand
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