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The occurrence of sleep-disordered breathing among middle-aged adults.
- T. Young, M. Palta, J. Dempsey, J. Skatrud, S. Weber, S. Badr
- MedicineThe New England journal of medicine
- 29 April 1993
The prevalence of undiagnosed sleep-disordered breathing is high among men and is much higher than previously suspected among women, and is associated with daytime hypersomnolence.
Epidemiology of obstructive sleep apnea: a population health perspective.
- T. Young, P. Peppard, D. Gottlieb
- MedicineAmerican journal of respiratory and critical care…
- 1 May 2002
Evidence from methodologically strong cohort studies indicates that undiagnosed obstructive sleep apnea, with or without symptoms, is independently associated with increased likelihood of hypertension, cardiovascular disease, stroke, daytime sleepiness, motor vehicle accidents, and diminished quality of life.
Increased prevalence of sleep-disordered breathing in adults.
- P. Peppard, T. Young, J. Barnet, M. Palta, E. Hagen, K. M. Hla
- MedicineAmerican journal of epidemiology
- 1 May 2013
The prevalence of sleep-disordered breathing in the United States for the periods of 1988-1994 and 2007-2010 is estimated using data from the Wisconsin Sleep Cohort Study, an ongoing community-based study with participants randomly selected from an employed population of Wisconsin adults.
Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index
Differences in leptin and ghrelin are likely to increase appetite, possibly explaining the increased BMI observed with short sleep duration, and changes in appetite regulatory hormones with sleep curtailment may contribute to obesity.
Longitudinal study of moderate weight change and sleep-disordered breathing.
The data indicate that clinical and public health programs that result in even modest weight control are likely to be effective in managing SDB and reducing new occurrence of SDB.
Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood…
Prospective study of the association between sleep-disordered breathing and hypertension.
A dose-response association between sleep-disordered breathing at base line and the presence of hypertension four years later was found that was independent of known confounding factors and suggest that sleep- disordered breathing is likely to be a risk factor for hypertension and consequent cardiovascular morbidity in the general population.
Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study.
A significant proportion of occult SDB in the general population would be missed if screening or case finding were based solely on increased body habitus or male sex, particularly in older adults.
Sleep-related breathing disorders in adults: Recommendations for syndrome definition and measurement techniques in clinical research
A CLOCK polymorphism associated with human diurnal preference.
It is suggested that the identified polymorphism or another tightly linked polymorphism within the CLOCK gene or its regulatory elements may be responsible for the finding of a substantial 10- to 44-minute delay in preferred timing for activity or sleep episodes.