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GPR expression in the rat taste bud relating to fatty acid sensing.
We investigated the expression of G protein-coupled receptor GPR40 and GPR120 in the rat tongue. Using reverse transcription polymerase chain reaction, we detected a significant expression of GPR120Expand
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Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
OBJECTIVES We sought to elucidate how the local activation of matrix metalloproteinases (MMPs) is balanced by that of the endogenous tissue inhibitors of MMP (TIMPs) during left ventricular (LV)Expand
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Combined Measurement of Fasting Plasma Glucose and A1C Is Effective for the Prediction of Type 2 Diabetes
OBJECTIVE We prospectively assessed whether the combined measurements of fasting plasma glucose (FPG) and A1C were effective for predicting type 2 diabetes. RESEARCH DESIGN AND METHODS StudyExpand
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Intragastric infusion of glucose enhances the rewarding effect of sorbitol fatty acid ester ingestion as measured by conditioned place preference in mice
We investigated substances that induce a rewarding effect during the postingestive process using the conditioned place preference (CPP) test. Although mice showed high affinity for a low-energy fatExpand
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The palatability of corn oil and linoleic acid to mice as measured by short-term two-bottle choice and licking tests
Free fatty acids (FFAs) were reported to be recognized in the oral cavity and possibly involved in fatty foods recognition. To understand the importance of oil recognition in the oral cavity, weExpand
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Liver Enzymes Compared With Alcohol Consumption in Predicting the Risk of Type 2 Diabetes
OBJECTIVE—It has been reported that moderate alcohol consumption decreased the risk of type 2 diabetes but that elevated liver enzymes increased it. The comparative importance of alcohol consumptionExpand
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Lower Serum Creatinine Is a New Risk Factor of Type 2 Diabetes
OBJECTIVE—Because skeletal muscle is one of the target tissues for insulin, skeletal muscle mass might be associated with type 2 diabetes. Serum creatinine is a possible surrogate marker of skeletalExpand
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Reinforcing effect for corn oil stimulus was concentration dependent in an operant task in mice.
Corn oil is reported to elicit a conditioned place preference (CPP) in a CPP test in mice. To further investigate a reinforcing effect of corn oil, we studied whether the corn oil acts as aExpand
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Reinduction of T-Type Calcium Channels by Endothelin-1 in Failing Hearts In Vivo and in Adult Rat Ventricular Myocytes In Vitro
Background—In ventricular myocardium, the T-type Ca2+ current (ICa,T), which is temporarily observed during fetal and neonatal periods, has been shown to reappear in failing/remodeling hearts.Expand
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Walking to Work Is an Independent Predictor of Incidence of Type 2 Diabetes in Japanese Men
Previous epidemiological studies have shown that vigorous physical activity reduces the development of type 2 diabetes (1–3). A recommendation from the Centers for Disease Control and PreventionExpand
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