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The Effect of Perceptual Learning on Neuronal Responses in Monkey Visual Area V4
Previous studies have shown that perceptual learning can substantially alter the response properties of neurons in the primary somatosensory and auditory cortices. Although psychophysical studiesExpand
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Physiological correlates of perceptual learning in monkey V1 and V2.
Performance in visual discrimination tasks improves with practice. Although the psychophysical parameters of these improvements have suggested the involvement of early areas in visual cortex, thereExpand
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HERG-Like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body.
Direct evidence for a specific K(+) channel underlying the resting membrane potential in glomus cells of the carotid body has been absent. The product of the human ether-a-go-go-related gene (HERG)Expand
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Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors.
Nicotine is an alkaloid that is used by large numbers of people. When taken into the body, it produces a myriad of physiological actions that occur primarily through the activation of neuronalExpand
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Chemosensing at the carotid body. Involvement of a HERG-like potassium current in glomus cells.
Currently, it is not clear what type of K+ channel(s) is active at the resting membrane potential (RMP) in glomus cells of the carotid body (CB). HERG channels produce currents that are known toExpand
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A role for primate subgenual cingulate cortex in sustaining autonomic arousal
Significance Dysregulation of emotion is central to the etiology of mood disorders, such as depression. A causal understanding of how neural structures regulate emotion and arousal could help toExpand
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The protein tyrosine kinase inhibitor, genistein, decreases excitability of nociceptive neurons
Abstract One mechanism by which neurons regulate their excitability is through ion channel phosphorylation. Compounds that increase nociceptive neuron excitability can cause hyperalgesia or allodyniaExpand
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Comment on “Single-trial spike trains in parietal cortex reveal discrete steps during decision-making”
Latimer et al. (Reports, 10 July 2015, p. 184) claim that during perceptual decision formation, parietal neurons undergo one-time, discrete steps in firing rate instead of gradual changes thatExpand
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Voltage-gated ion channels in nociceptors: modulation by cGMP.
In tissue or nerve injury, proinflammatory mediators are released that can modulate a variety of ion channels found in nociceptors. The changes in channel activity, which primarily occurs throughExpand
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Is ZD7288 a selective blocker of hyperpolarization-activated cyclic nucleotide-gated channel currents?
ZD7288 has been widely used as a tool in the study of hyperpolarization-activated cyclic nucleotide-gated channels (HCN channels), and to test the relationships between HCN channels and heart andExpand
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