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Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
“Lysosomal glycogen storage disease with normal acid maltase”, which was originally described by Danon et al., is characterized clinically by cardiomyopathy, myopathy and variable mental retardation.… Expand
Lamin B1 duplications cause autosomal dominant leukodystrophy
NOTE: The construct we described as moody-GAL4 has a name that was assigned to a different construct in a previously published paper. In this paper, it should be referred to as SPG-GAL4 (for… Expand
The roles of the C-terminal domain and type III domains of chitinase A1 from Bacillus circulans WL-12 in chitin degradation.
- T. Watanabe, Y. Ito, T. Yamada, M. Hashimoto, S. Sekine, H. Tanaka
- Biology, Medicine
- Journal of bacteriology
- 1 August 1994
The mature form of chitinase A1 from Bacillus circulans WL-12 comprises a C-terminal domain, two type III modules (domains), and a large N-terminal domain which contains the catalytic site of the… Expand
Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat.
We systematically characterized the levels and substrate specificity of P450s from humans and rats to extrapolate drug metabolism data from experimental animals to humans. Human P450s (CYP1A2, 2A6,… Expand
Physical and Functional Interactions of the Lysophosphatidic Acid Receptors with PDZ Domain-containing Rho Guanine Nucleotide Exchange Factors (RhoGEFs)*
Lysophosphatidic acid (LPA) is a serum-derived phospholipid that induces a variety of biological responses in various cells via heterotrimeric G protein-coupled receptors (GPCRs) including LPA1,… Expand
Involvement of oxygen-sensitive pyruvate formate-lyase in mixed-acid fermentation by Streptococcus mutans under strictly anaerobic conditions.
Streptococcus mutans JC2 produced formate, acetate, ethanol, and lactate when suspensions were incubated with an excess of galactose or mannitol under strictly anaerobic conditions. The galactose- or… Expand
Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
Two new lanostane-type triterpenoids, inonotsuoxides A (1) and B (2) along with three known lanostane-type triterpenoids, inotodiol (3), trametenolic acid (4), and lanosterol (5), were isolated from… Expand
Hydrogen peroxide excretion by oral streptococci and effect of lactoperoxidase-thiocyanate-hydrogen peroxide.
Approved type strains of Streptococcus sanguis, S. mitis, S. mutans, and S. salivarius were grown under aerobic and anaerobic conditions. The rate of hydrogen peroxide excretion, oxygen uptake, and… Expand
Cytotoxic cytochalasans from a Penicillium species separated from a marine alga
Abstract New cytochalasans, penochalasins D–H, have been isolated along with chaetoglobosin O from a strain of Penicillium sp. originally separated from the marine alga Enteromorpha intestinalis ,… Expand
Regulation of lactate dehydrogenase and change of fermentation products in streptococci.
Streptococcus mutans JC 2 produced mainly lactate as a fermentation product when grown in nitrogen-limited continuous culture in the presence of an excess of glucose and produced formate, acetate,… Expand