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IL-17F gene polymorphism is associated with susceptibility to acute myeloid leukemia
TLDR
The rs763780 IL-17F polymorphism was found to be associated with predisposition to AML in the Polish population.
Early Administration of Convalescent Plasma Improves Survival in Patients with Hematological Malignancies and COVID-19
TLDR
It is demonstrated that convalescent plasma is an effective treatment and its early administration leads to clinical improvement, increased viral clearance and longer overall survival in patients with hematological malignancies and COVID-19.
Pharmacokinetics of high-dose i.v. treosulfan in children undergoing treosulfan-based preparative regimen for allogeneic haematopoietic SCT
TLDR
Variation of pharmacokinetic results observed in children studied demonstrates the need for pharmacokinetics evaluation in each paediatric patient undergoing the treosulfan-based preparative regimen, including those using different doses, and could enable further reduction of the risk of early and late organ toxicity related to high-dose treosolfan in paediatric patients.
Gastrointestinal non-Hodgkin lymphomas.
TLDR
In this review, clinical and pathological features of GI lymphomas are presented and the current status in diagnosis and treatment is described.
Increased angiogenesis in cutaneous T-cell lymphomas
TLDR
Increased MVD in the skin of CTCL patients indicate that angiogenesis may play a role in the growth of C TCL, and raises the possibility of using angiogenic inhibitors in CTCl therapy.
Lack of association between the TNF‐α promoter gene polymorphism and susceptibility to B‐cell chronic lymphocytic leukaemia
TLDR
Whether there is an association between the polymorphic features located within the promoter/enhancer region of tumour necrosis factor‐α (TNFA) gene and susceptibility to B‐CLL is investigated.
Variations in genes involved in regulation of the nuclear factor – κB pathway and the risk of acute myeloid leukaemia
TLDR
Polymorphisms within the TLR9 and TRAF3 genes are associated with predisposition to AML and may affect the progression of the disease in the Polish population.
Role of the functional MNS16A VNTR‐243 variant of the human telomerase reverse transcriptase gene in progression and response to therapy of patients with non‐Hodgkin's B‐cell lymphomas
TLDR
Investigation of whether any of the MNS16A repeats represents a genetic risk factor for NHL susceptibility, progression of or response to therapy in 75 patients with non‐Hodgkin's lymphomas and 126 healthy individuals found independent genetic markers associated with nonresponse to treatment.
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