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Molecular diffusion measurement in lipid bilayers over wide concentration ranges: a comparative study.
Molecular diffusion in biological membranes is a determining factor in cell signaling and cell function. In the past few decades, three main fluorescence spectroscopy techniques have emerged that areExpand
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Phosphatidylserine dynamics in cellular membranes
The distribution and dynamics of phosphatidylserine are studied in the plasma membrane and in organellar membranes of live cells using two novel fluorescent probes in combination with variousExpand
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Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy.
Single wavelength fluorescence cross-correlation spectroscopy (SW-FCCS), introduced to study biomolecular interactions, has recently been reported to monitor enzyme activity by using a newlyExpand
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Spatially resolved total internal reflection fluorescence correlation microscopy using an electron multiplying charge-coupled device camera.
A spatially resolved total internal reflection fluorescence correlation microscopy (TIR-FCM) system is constructed with an electron multiplying charge-coupled device (EMCCD) camera. The system wasExpand
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Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish
BackgroundEarly events in vertebrate liver development have been the major focus in previous studies, however, late events of liver organogenesis remain poorly understood. Liver vasculogenesis inExpand
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Single plane illumination fluorescence correlation spectroscopy (SPIM-FCS) probes inhomogeneous three-dimensional environments.
The life sciences require new highly sensitive imaging tools, which allow the quantitative measurement of molecular parameters within a physiological three-dimensional (3D) environment. Therefore, weExpand
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A fluorescent sphingolipid binding domain peptide probe interacts with sphingolipids and cholesterol-dependent raft domainss⃞s⃞ The online version of this article (available at http://www.jlr.org)
We have designed a tagged probe [sphingolipid binding domain (SBD)] to facilitate the tracking of intracellular movements of sphingolipids in living neuronal cells. SBD is a small peptide consistingExpand
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  • Open Access
ImFCS: a software for imaging FCS data analysis and visualization.
The multiplexing of fluorescence correlation spectroscopy (FCS), especially in imaging FCS using fast, sensitive array detectors, requires the handling of large amounts of data. One can easilyExpand
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  • Open Access
Factors affecting the quantification of biomolecular interactions by fluorescence cross-correlation spectroscopy.
Fluorescence cross-correlation spectroscopy (FCCS) is used to determine interactions and dissociation constants (K(d)s) of biomolecules. The determination of a K(d) depends on the accurateExpand
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Interaction of an artificial antimicrobial peptide with lipid membranes.
Antimicrobial peptides constitute an important part of the innate immune defense and are promising new candidates for antibiotics. Naturally occurring antimicrobial peptides often possess hemolyticExpand
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