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Sex and virulence in Escherichia coli: an evolutionary perspective
The evolution of virulence is linked to bacterial sex because rates of evolution have accelerated in pathogenic lineages, culminating in highly virulent organisms whose genomic contents are altered frequently by increased rates of homologous recombination. Expand
Traces of Human Migrations in Helicobacter pylori Populations
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations deriveExpand
Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity
The phylogenetic analysis suggests that Y. pestis evolved in or near China and spread through multiple radiations to Europe, South America, Africa and Southeast Asia, leading to country-specific lineages that can be traced by lineage-specific SNPs. Expand
Microevolution and history of the plague bacillus, Yersinia pestis.
An evolutionary tree is proposed for these populations, rooted on Yersinia pseudotuberculosis, which invokes microevolution over millennia, during which enzootic pestoides isolates evolved and led to populations that are more frequently associated with human disease. Expand
A New Perspective on Listeria monocytogenes Evolution
This work provides a reference evolutionary framework for future studies on L. monocytogenes epidemiology, ecology, and virulence, with convergent evolution indicative of natural selection towards a truncation of InlA protein. Expand
Genetic evidence against panmixia in the European eel
Analysis of seven microsatellite loci among 13 samples from the north Atlantic, the Baltic Sea and the Mediterranean Sea basins reveals that there is global genetic differentiation, which implies non-random mating and restricted gene flow among eels from different sampled locations, which refute the hypothesis of panmixia. Expand
Origin, Spread and Demography of the Mycobacterium tuberculosis Complex
It is shown that the Mycobacterium tuberculosis complex consists of two independent clades, one composed exclusively of M. tuberculosis lineages from humans and the other composed of both animal and human isolates, supporting the hypothesis of an original human host. Expand
A Timescale for Evolution, Population Expansion, and Spatial Spread of an Emerging Clone of Methicillin-Resistant Staphylococcus aureus
This work investigates an MRSA strain that is highly prevalent in hospitals in Central Europe and reconstructs its recent demographic history and the spatiotemporal dynamics of spread, finding extremely low diversity among European ST225 isolates, indicating that a recent population bottleneck had preceded the expansion of this clone. Expand
Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological Study
In an outbreak investigation of Mycobacterium tuberculosis comparing whole genome sequencing (WGS) with traditional genotyping, Stefan Niemann and colleagues found that classical genotyping falselyExpand
Comparative Microsatellite Typing of New World Leishmania infantum Reveals Low Heterogeneity among Populations and Its Recent Old World Origin
It is confirmed that the agent of VL in the NW is L. infantum and that the parasite has been recently imported multiple times to the NW from southwest Europe. Expand