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Group-transfer polymerization. 1. A new concept for addition polymerization with organosilicon initiators
Polymerisation du methacrylate de methyle avec l'acetal de dimethylcetone methyl trimethylsilyle. Reaction rapide a temperature ambiante conduisant a un polymere vivant de distribution etroite de la
Ligand Electronic Effects in Asymmetric Catalysis - Enhanced Enantioselectivity in the Asymmetric Hydrocyanation of Vinylarenes
The enantioselectivity of the nickel-catalyzed, asymmetric hydrocyanation of vinylarenes using glucose- derived, chiral phosphinite ligands, L, increases dramatically when the ligands contain
Reactivity and selectivity in hydrovinylation of strained alkenes.
The scope of Ni(II)-catalyzed hydrovinylation has been extended to strained alkenes such as heterobicyclic [2.2.1]heptanes and cylobutenes, giving excellent yield and one of the highest enantioselectivities reported for a C-C bond-forming reaction of norbornenes.
Conformation and reactivity in dibenzocyclooctadienes (DBCOD). A general approach to the total synthesis of fully substituted DBCOD lignans via borostannylative cyclization of α,ω-diynes
Dibenzocyclooctadienes (DBCOD) are a class of plant-derived natural products that exhibit a broad range of biological activities. These include cytotoxicity, anti-hepatitis-B activity, inhibition of
Selective Generation of Free Radicals from Epoxides Using a Transition-Metal Radical. A Powerful New Tool for Organic Synthesis
Bis(cycIopentadienyl)titanium(III) chloride reacts with epoxides by initial C-0 homolysis. The regiochemistry of the opening is determined by the relative stabilities of the radicals. Depending on
Asymmetric hydrovinylation reaction.
The catalytic dimerization of propene proceeds with an astonishingly high rate of over 625 000 [propene][Ni]-1 [h]-1 for the precatalyst, making this one of the best homogeneously catalyzed reactions known.
Control of Selectivity through Synergy between Catalysts, Silanes and Reaction Conditions in Cobalt-Catalyzed Hydrosilylation of Dienes and Terminal Alkenes.
Mechanistic studies suggest a pathway that involves a key role for an in situ generated metal hydride, (L)Co(I)-H, in the decomposition path for the linear Co(I-alkyl intermediate.
Transition-metal-centered radicals in organic synthesis. Titanium(III)-induced cyclization of epoxy olefins
We wish to report a solution to this problem which allows the direct synthesis of functionalized cyclopentane derivatives. This new reaction is based on an analogy to the extremely facile
Enantioselective desymmetrization of meso-aziridines with TMSN3 or TMSCN catalyzed by discrete yttrium complexes.
using a variety ofnucleophiles have been the subject of extensive research. Theless developed ring-opening reactions, those of meso-aziri-dines by carbon and nitrogen nucleophiles, give direct
Asymmetric hydrovinylation of unactivated linear 1,3-dienes.
In sharp contrast to the corresponding Ni(II)-catalyzed hydrovinylation, 1-aryl-substituted 1,3-dienes give almost exclusively achiral linear 1,4-addition products, unless the 2-position is also substituted.