• Publications
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The three-dimensional organization of collagen fibrils in the human cornea and sclera.
  • Y. Komai, T. Ushiki
  • Materials Science, Medicine
    Investigative ophthalmology & visual science
  • 1 July 1991
The organization of collagen fibrils in the human cornea and sclera was studied by scanning electron microscopy, after digestion of cellular elements by sodium hydroxide, and by conventional
Collagen fibers, reticular fibers and elastic fibers. A comprehensive understanding from a morphological viewpoint.
  • T. Ushiki
  • Materials Science, Medicine
    Archives of histology and cytology
  • 1 June 2002
TLDR
The fibrous components of the extracellular matrix are thereby morphologically categorized into two systems: the collagen fibrillar system as a supporting framework of tissues and cells, and the microfibrilelastin system for uniformly distributing stress to maintain the resilience adapted to local tissue requirements.
Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells.
TLDR
A role for Scc1 in mitotic regulation, along with cohesion is suggested, although temporal differences exist between eukaryotes in cohesin loss from chromosome arms, as distinct from centromeres.
Elasticity mapping of living fibroblasts by AFM and immunofluorescence observation of the cytoskeleton.
TLDR
A comparison between the AFM and the CLSM images revealed that the elasticity of the cells was concerned not only with the distribution of actin network, but also with intermediate filaments, whereas microtubules had no large effect on the measured elasticity.
Structural changes of collagen components and diminution of nerves in congenital ureteropelvic junction obstruction.
TLDR
In the intrinsic obstruction, nerve fibers were depleted in the muscular layers in the ureteric walls, resulting in dysfunction and atrophy of muscle fibers and an increase of collagen fibers in the muscle layers with abnormal accumulation of intercellular and interstitial collagen.
The subfibrillar arrangement of corneal and scleral collagen fibrils as revealed by scanning electron and atomic force microscopy.
TLDR
The present study showed that corneal collagen fibrils differ from scleral collagenFibrils not only in diameter but also in substructure, indicating that the different D-periodicity between corneals depends on the different inclinations of the subfibrils in each fibril.
Myosin-Va regulates exocytosis through the submicromolar Ca2+-dependent binding of syntaxin-1A.
TLDR
The results demonstrate that the interaction between myosin-Va and syntaxin-1A is involved in exocytosis and suggest that the myosIn-Va neck contributes not only to the large step size but also to the regulation of exocyTosis by Ca2+.
Chromosome Binding Site of Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Is Essential for Persistent Episome Maintenance and Is Functionally Replaced by Histone H1
TLDR
The results suggest that tethering of KSHV episomes to mitotic chromosomes by LANA1 is crucial in mediating the long-term maintenance of viral episomes in dividing cells.
Three-dimensional organization of the collagen fibrils in the rat sciatic nerve as revealed by transmission- and scanning electron microscopy
  • T. Ushiki, C. Ide
  • Materials Science, Medicine
    Cell and Tissue Research
  • 1 April 1990
TLDR
The collagen fibril arrangement in the rat sciatic nerve may protect the nerve fibers against external forces.
Distribution and ultrastructure of the autonomic nerves in the mouse pancreas
TLDR
The intrapancreatic nerves formed four plexuses: perivascular, periductal, periacinar and peri‐insular, which were networks of unmyelinated nerve fibers consisting of axons with varicosities and Schwann cells.
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