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- Publications
- Influence
STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas.
- N. Sato, C. Rosty, +7 authors M. Goggins
- Biology, Medicine
- The American journal of pathology
- 1 December 2001
Despite the growing awareness of intraductal papillary-mucinous neoplasms (IPMNs) of the pancreas among clinicians, the molecular features of IPMNs have not been well characterized. Previous reports… Expand
Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.
- C. Rosty, T. Ueki, +5 authors M. Goggins
- Biology, Medicine
- The American journal of pathology
- 2002
Using the National Center for Biotechnology Information Serial Analysis of Gene Expression database, we found that S100A4, a calcium-binding protein previously implicated in metastasis, was expressed… Expand
Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
- Noriyoshi Fukushima, N. Sato, +6 authors M. Goggins
- Biology, Medicine
- The American journal of pathology
- 1 May 2002
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have previously shown that the preproenkephalin (ppENK) and p16 genes are… Expand
Intraductal papillary mucinous neoplasms of the pancreas associated with so-called "mucinous ductal ectasia". Histochemical and immunohistochemical analysis of 29 cases.
- E. Nagai, T. Ueki, K. Chijiiwa, M. Tanaka, M. Tsuneyoshi
- Medicine
- The American journal of surgical pathology
- 1 May 1995
Twenty-nine patients (20 men, nine women; mean age, 65.9 years; range, 49-77 years) with intraductal papillary mucinous neoplasms associated with so-called "mucinous ductal ectasia" of the pancreas… Expand
Genetic Polymorphisms of XRCC1, Alcohol Consumption, and the Risk of Colorectal Cancer in Japan
- Guang Yin, M. Morita, +15 authors Reiji Terasaka
- Medicine
- Journal of epidemiology
- 17 December 2011
Background X-ray cross-complementing group 1 (XRCC1) polymorphisms affect DNA repair capacity and may therefore be of importance in colorectal carcinogenesis. Alcohol consumption, an important risk… Expand
K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in China.
- A. Rashid, T. Ueki, +6 authors A. Hsing
- Biology, Medicine
- Clinical cancer research : an official journal of…
- 1 October 2002
PURPOSE
The genetic alterations in biliary tract cancer and clinicopathological associations have not been studied in large population-based studies.
EXPERIMENTAL DESIGN
We evaluated genetic… Expand
Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas.
- N. Sato, T. Ueki, +5 authors M. Goggins
- Biology, Medicine
- Gastroenterology
- 1 July 2002
BACKGROUND & AIMS
The functional abrogation of several tumor suppressor genes, including p16, DPC4, and p53, is a major mechanism underlying pancreatic ductal carcinogenesis. However, mutational… Expand
Accelerated rejection of Fas ligand-expressing heart grafts.
- T. Takeuchi, T. Ueki, +8 authors T. Kitamura
- Medicine
- Journal of immunology
- 1999
The Fas/Fas ligand (FasL) system plays an important role in the induction of lymphoid apoptosis and has been implicated in the suppression of immune responses. Recently, there has been renewed… Expand
Associations between vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk and effect modifications of dietary calcium and vitamin D in a Japanese population.
- N. Takeshige, Guang Yin, +11 authors Reiji Terasaka
- Medicine
- Asian Pacific journal of cancer prevention…
- 2015
Much interest has been drawn to possible associations between vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk in conjunction with potentially protective effects of calcium and… Expand
Diagnosing Pancreatic Cancer Using Methylation Specific PCR Analysis
- Noriyoshi Fukushima, K. Walter, +7 authors M. Goggins
- Medicine
- Cancer biology & therapy
- 1 January 2003
The aim of this study was to determine the utility of detecting methylated ppENK and p16 in pancreatic juice by methylation specific PCR as a marker of pancreatic adenocarcinoma. Pancreatic juice… Expand