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Preparation and Hydrolysis of 4-Amino-1H-1, 5-benzodiazepine-3-carbonitrile
In the presence of hydrochloric acid, o-(2, 2-dicyanovinyl) aminoaniline is easily converted into 4-amino-1H-1, 5-benzodiazepine-3-carbonitrile, which can be hydrolyzed with various bases to other… Expand
Syntheses and Antimicrobial Activity of 2-Acylaminothiazole-carboxylic Acid and its Related Compounds
Syntheses of 2-acylaminoacetamidine and 3-acylaminopropionamidine derivatives.
- T. Ueda, Y. Okamoto, T. Tsuji, M. Muraoka
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 25 December 1968
For the purpose to examine as to their antiviral activities, 2-acylaminoacetamidine (II) and 3-acylaminopropionamidine hydrochlorides (III) were synthesized from the corresponding nitriles via ethyl… Expand
Reaction of Triethyloxonium Fluoroborate with Acid Amide. I. Formation of Cyclic Amidine and Tetrahydropyrimidine
Because several series of compounds having amidine moieties that had been synthesized had a marked effect on influenza viruses in mice, iminoesterification by the reaction of amides with… Expand
Antiviral effect of guanidine and its derivatives. I. The inhibitory effect of guanidine on the multiplication of poliomyelitis virus in tissue culture.
Inhibitory effect of halogenated pyrimidines on multiplication of viruses in tissue culture systems.
It is of interest to examine the inhibitory effect of halogenated pyrimidines on the multiplication of viruses in tissue culture systems, in view of finding the fundamental knowledge to obtain… Expand
SYNTHESES OF 2-GUANIDINO-2-METHYLPROPYLAMINE DERIVATIVES.
The polyamines which were obtained by the hydrogenation of N-substituted 2-methyl-2-nitropropylamines, were derived to the corresponding guanidine derivatives with S-methylisothiourea sulfate. Some… Expand
Influence of 5-Fluorodeoxyuridine on the Cell-infective Unit of Adeno Virus in HeLa Cells
WE have already reported that several halogenated pyrimidines including 5-fluorodeoxyuridine (FUDR) did not show a complete inhibition of the multiplication of adeno type 1 virus in the experiments… Expand