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Adaptive bone remodeling around bonded noncemented total hip arthroplasty: A comparison between animal experiments and computer simulation
The detailed comparison showed that long‐term changes in the morphology of bone around femoral components of total hip replacements can be fully explained with the present quantitative adaptive bone‐remodeling theory. Expand
ESB Research Award 1992. The mechanism of bone remodeling and resorption around press-fitted THA stems.
The simulation models predicted similar amounts of proximal bone loss and distal bone densification as found in the animal model, suggesting that the cortical bone loss could indeed be predicted by the strain-adaptive bone remodeling theory. Expand
Use of a calcium sulfate-based bone graft substitute for benign bone lesions.
Calcium sulfate is a well-tolerated, biodegradable, osteoconductive bone graft substitute and a reasonable alternative to autogenous bone graft for benign bone lesions. Expand
Increased Bone Formation Using Calcium Sulfate-Calcium Phosphate Composite Graft
This novel CaSO4/CaPO4 composite holds promise for clinical applications where a strong, injectable, slower-resorbing, and biocompatible bone graft substitute would be advantageous. Expand
Enhancement of bone ingrowth by transforming growth factor-beta.
The data from the present investigation indicate that enhancement of bone ingrowth in implants that have been treated with a combination of a hydroxyapatite-tricalcium phosphate coating and transforming growth factor-beta 1 may exceed that obtainable with grafting of the gap with autogenous cancellous bone. Expand
A comparative study of porous coatings in a weight-bearing total hip-arthroplasty model.
In all groups, a proximal-to-distal gradient of loss of cortical bone was observed by six months, and the group of dogs that had the stem with the circumferential coating experienced more severe loss of bone than did the three groups that had a stem with a partial coating. Expand
A five-year study of 221 total hip replacements in the dog.
Radiographic and Histologic Assessment of Calcium Sulfate in Experimental Animal Models and Clinical Use as a Resorbable Bone-Graft Substitute, a Bone-Graft Expander, and a Method for Local
Evaluating healing after the use of calcium sulfate as a synthetic bone graft compared with spontaneous healing with no graft material and healing after use of autogenous bone graft in a large medullary defect model shows consistent osteoconduction, excellent biocompatibility, and complete resorption of calcium sulfur. Expand
Locally delivered rhBMP‐2 enhances bone ingrowth and gap healing in a canine model
Application of rhBMP‐2 to a porous‐coated implant stimulated local bone ingrowth and gap healing and the enhancement of bone formation within the implant (bone ingrowth) was inversely related to dose. Expand
The use of acellular dermal matrix as a scaffold for periosteum replacement.
Three preclinical models were used to evaluate GraftJacket Acellular Periosteum Replacement Scaffold and provided preliminary evidence that the dermal membrane material may be used as a scaffold for periostEum regeneration by allowing for cellular repopulation, revascularization, and bone defect restoration. Expand