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- Publications
- Influence
KATP channel modulation in working rat hearts with coronary occlusion: effects of cromakalim, cicletanine, and glibenclamide.
- P. Ferdinandy, Z. Szilvássy, M. T. Droy-lefaix, T. Tarrade, M. Koltai
- Medicine
- Cardiovascular research
- 1 November 1995
OBJECTIVES
We studied the effects of ATP-sensitive potassium channel (KATP) modulation on ischemic cardiac performance and reperfusion-induced ventricular fibrillation (VF), and assessed the… Expand
Regional localization of patterned spontaneous discharges during maturation in culture of fetal mouse medulla and spinal cord explants.
- T. Tarrade, S. Crain
- Biology, Medicine
- Developmental neuroscience
- 1978
Development and regional localization of patterned spontaneous bioelectric activities, recorded extracellularly, were studied in cultures of frontal sections of spinal cord and medulla, explanted… Expand
Psychopharmacological effects of Ginkgo Biloba extract (EGb 761) In healthy volunteers
- L. Lacomblez, D. Warot, T. Tarrade, A. Puech
- Chemistry
- 1 July 1990
α2‐Adrenoceptor Changes During Cerebral Ageing. The Effect of Ginkgo biloba Extract
- F. Huguet, T. Tarrade
- Biology, Medicine
- The Journal of pharmacy and pharmacology
- 1 January 1992
Abstract— [3H]Rauwolscine binding to α2‐adrenoceptors in cerebral cortex and hippocampus membranes of young (4 months) and aged (24 months) Wistar rats has been investigated. In aged rats, Bmax… Expand
Efficacy and tolerance of cicletanine, a new antihypertensive agent: overview of 1226 treated patients.
- T. Tarrade, P. Guinot
- Medicine
- Drugs under experimental and clinical research
- 1988
The data gathered from 1226 patients for 20 controlled therapeutic studies performed during the phase-III development of cicletanine, a new antihypertensive agent, were pooled in a computerized… Expand
UV-C irradiation-induced peroxidative degradation of microsomal fatty acids and proteins: protection by an extract of Ginkgo biloba (EGb 761).
- E. Dumont, E. Petit, T. Tarrade, A. Nouvelot
- Chemistry, Medicine
- Free radical biology & medicine
- 1 September 1992
After exposure of rat liver microsomes to UV-C irradiation, analysis of membrane fatty acids by gas chromatography confirmed that EGb 761, a drug containing a dosed and standardized extract of Ginkgo… Expand
Cicletanine Improves Myocardial Function Deteriorated by Ischemia/Reperfusion in Isolated Working Rat Hearts
- P. Ferdinandy, M. Koltai, +4 authors P. Braquet
- Medicine
- Journal of cardiovascular pharmacology
- 1 February 1992
Summary The effect of cicletanine, a novel furopyridine antihypertensive drug was compared with that of nitren-dipine, a dihydropyridine slow calcium channel blocker, on cardiac function and… Expand
Cicletanine attenuates overdrive pacing‐induced global myocardial ischemia in rabbits: possible role of cardiac cyclic nucleotides
- Z. Szilvássy, I. Jakab, +5 authors J. Lonovics
- Medicine
- Coronary artery disease
- 1 May 1993
BackgroundThis study examined whether cicletanine, an antihypertensive drug with cGMP phosphodiesterase inhibitory effect, could alleviate ventricular overdrive pacing-induced myocardial ischemia in… Expand
Effect of cicletanine on reperfusion-induced arrhythmias and myocardial ion contents: a comparison with furosemide.
- M. Koltai, A. Tosaki, P. Berthet, T. Tarrade, A. Esanu, P. Braquet
- Medicine
- European heart journal
- 1 March 1992
We studied the effects of cicletanine, a furopyridine antihypertensive drug, and furosemide, a loop diuretic, on ventricular arrhythmias, such as sustained ventricular fibrillation (VF) and… Expand
Protective Effect of Cicletanine on Hypertension‐Induced Decreases in the Renal Kallikrein‐Kinin and Prostaglandin Systems in Stroke‐Prone Spontaneously Hypertensive Rats
- C. Emond, G. Bompart, +6 authors J. P. Girolami
- Medicine
- Journal of cardiovascular pharmacology
- 1 October 1992
Summary: We investigated the effect of two oral (p.o.) doses of cicletanine (5 and 30 mg/kg/day) for 4 weeks on urinary excretion (UKE), renal concentration (RKC) of kallikrein, and prostaglandin E2… Expand