Exciton chirality method in vibrational circular dichroism.
This method can analyze various molecules whose absolute configuration is difficult to determine by other spectroscopic methods, but also it can significantly enhance VCD signals.
Genome Mining for Sesterterpenes Using Bifunctional Terpene Synthases Reveals a Unified Intermediate of Di/Sesterterpenes.
- Y. Ye, A. Minami, H. Oikawa
- Chemistry, BiologyJournal of the American Chemical Society
- 4 September 2015
The Aspergillus oryzae heterologous expression system was applied to functionally characterize cryptic bifunctional terpene synthase genes found in fungal genomes and the sesterfisherol synthase gene (NfSS) from Neosartorya fischeri was identified.
Structural diversity of new C13-polyketides produced by Chaetomium mollipilium cultivated in the presence of a NAD(+)-dependent histone deacetylase inhibitor.
Spectroscopic methods, X-ray single crystal diffraction analysis, and VCD elucidated the absolute configurations of structures 1-6, and plausible biosynthetic pathways for 1-7 were proposed based on structural relationships.
Effects of central metal ions on vibrational circular dichroism spectra of tris-(beta-diketonato)metal(III) complexes.
- Hisako Sato, T. Taniguchi, A. Nakahashi, K. Monde, A. Yamagishi
- ChemistryInorganic Chemistry
- 11 July 2007
The VCD spectrum can probe the effect of the central metal ion on interligand cooperative vibration modes and implies that the energy levels of C-O stretches are delicately affected by the kind of central metal ions.
Structures of spiroindicumides A and B, unprecedented carbon skeletal spirolactones, and determination of the absolute configuration by vibrational circular dichroism exciton approach.
- Teigo Asai, T. Taniguchi, Takashi Yamamoto, K. Monde, Y. Oshima
- ChemistryOrganic Letters
- 23 August 2013
This study presents the first application of the VCD exciton approach to novel natural products, isolated from a filamentous fungus and cultivated in the presence of a histone deacetylase inhibitor.
Focused Genome Mining of Structurally Related Sesterterpenes: Enzymatic Formation of Enantiomeric and Diastereomeric Products.
Their structures suggested that formation of the products occurs via various diastereomeric carbocation intermediates, allowing the proposal that clade-A BFTSs catalyze three-step cyclizations using several stereofacial combinations of allylic cation-olefin pairs in the corresponding intermediates to generate various stereoisomers.
Dihydrobenzofurans as cannabinoid receptor ligands from Cordyceps annullata, an entomopathogenic fungus cultivated in the presence of an HDAC inhibitor
In Depth Study on Solution-State Structure of Poly(lactic acid) by Vibrational Circular Dichroism
It is demonstrated that vibrational circular dichroism (VCD) spectroscopy can conveniently and accurately elucidate the conformation of polyesters through the studies on poly(l-lactic acid) (PLLA), PLLA-amylose complex, and oligo( l- lactic acid).
Chiral cruciferous phytoalexins: preparation, absolute configuration, and biological activity.
Short synthesis of berkeleyamide D and determination of the absolute configuration by the vibrational circular dichroism exciton chirality method.
- Kenta Komori, T. Taniguchi, Shoma Mizutani, K. Monde, K. Kuramochi, K. Tsubaki
- ChemistryOrganic Letters
- 14 February 2014
The first synthesis of (±)-berkeleyamide D has been accomplished and the absolute configurations of both enantiomers of ber Berkeleyamide D were determined by the vibrational circular dichroism exciton chirality method.