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Genome evolution in the allotetraploid frog Xenopus laevis
To explore the origins and consequences of tetraploidy in the African clawed frog, we sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis genome. We characterizeExpand
The Cytoplasmic Shuttling and Subsequent Degradation of p27Kip1 Mediated by Jab1/CSN5 and the COP9 Signalosome Complex*
The fifth component of the COP9 signalosome complex, Jab1/CSN5, directly binds to and induces specific down-regulation of the cyclin-dependent kinase inhibitor p27 (p27Kip1). Nuclear-cytoplasmicExpand
Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer
Japanese mortality due to colorectal cancer is on the rise, surpassing 49,000 in 2015. Many new treatment methods have been developed during recent decades. The Japanese Society for Cancer of theExpand
On the Existence of 3-Round Zero-Knowledge Protocols
We construct a 3-round zero-knowledge protocol for any NP language. Expand
Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles.
Preoperative radiotherapy has been widely used to improve local control of disease and to improve survival in the treatment of rectal cancer. However, the response to radiotherapy differs amongExpand
Pioglitazone improves insulin secretory capacity and prevents the loss of beta-cell mass in obese diabetic db/db mice: Possible protection of beta cells from oxidative stress.
In order to assess the beneficial effect of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist pioglitazone on reduction of mass and alteration of function of pancreatic betaExpand
Regulation of Notch Signaling by Dynamic Changes in the Precision of S3 Cleavage of Notch-1
ABSTRACT Intramembrane proteolysis by presenilin-dependent γ-secretase produces the Notch intracellular cytoplasmic domain (NCID) and Alzheimer disease-associated amyloid-β. Here, we show that uponExpand
The new concept 3-way catalyst for automotive lean-burn engine: NOx storage and reduction catalyst
The new concept 3-way catalysts for a lean-burn engine have been developed, and their NOx purification mechanisms have been studied. The catalysts consist of precious metals, aluminum oxide and someExpand
Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor
Maturation/M-phase-promoting factor is the universal inducer of M-phase in eukaryotic cells. It is currently accepted that M-phase-promoting factor is identical to the kinase cyclin B–Cdk1. Here weExpand
A New (k, n)-Threshold Secret Sharing Scheme and Its Extension
In Shamir's (k,n)-threshold secret sharing scheme (threshold scheme), a heavy computational cost is required to make nshares and recover the secret, but every group of less than kparticipants cannot obtain any information about the secret. Expand