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Site-specific expression of mRNAs for osteonectin, osteocalcin, and osteopontin revealed by in situ hybridization in rat periodontal ligament during physiological tooth movement.
We investigated the gene expression for non-collagenous proteins in periodontal ligament (PDL) by in situ hybridization histochemistry with a non-radioisotopic probe with cRNAs for osteocalcin (Osc),Expand
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Alterations in the expression of osteonectin, osteopontin and osteocalcin mRNAs during the development of skeletal tissues in vivo.
Heterogeneity in the expression of three members of non-collagenous matrix proteins in osteogenic and chondrogenic development in vivo were investigated by in situ hybridization. Sections of severalExpand
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Method for detecting the expression of bone matrix protein by in situ hybridization using decalcified mineralized tissue
The sensitive and high resolution method of in situ hybridization technique has been developed using digoxigenin-11 UTP labeled cRNA as a probe. The system was applied to the decalcified mineralizedExpand
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Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization
The expression of the mRNAs for osteonectin (ON), osteopontin (OPN), osteocalcin (OC), and matrix Gla protein (MGP) was studied by in situ hybridization during the healing process of an experimentalExpand
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Expression of vascular permeability factor (VPFNEGF) messenger RNA by plasma cells: Possible involvement in the development of edema in chronic inflammation
Edema occurs in some types of chronic inflammation such as nasal polyps, uterine cervical polyps and gastric hyper‐plastic polyps. However, the factors or cellular components involved in theExpand
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Localization of osteopontin in the otoconial organs of adult rats
Although it is known that mammalian otoconia consist of calcium bicarbonate and organic materials, none of the protein components have been identified in mammals at the molecular level, and theExpand
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Localization of bone morphogenetic protein-4 messenger RNA in developing mouse cochlea
Bone morphogenetic protein-4 (BMP-4) is a cytokine that belongs to the TGF-beta superfamily. It has been implicated that it plays an important role during embryogenesis includingExpand
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Expression of mRNA of murine bone-related proteins in ectopic bone induced by murine bone morphogenetic protein-4
To determine whether a system of ectopic bone formation induced by osteosarcoma-derived bone-inducing substance (bone morphogenetic protein-4) can be used as a model of developing bone at theExpand
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[Application of non-radioisotopic in situ hybridization to the inner ear--expression of osteopontin].
Osteopontin (OPN) is considered to be a non-collagenous bone matrix protein which is involved in the ossification process. However, OPN has recently been observed in ectopic sites such as the kidneyExpand
APPLICATION OF NON-RADIOISOTOPIC IN SITUHYBRIDIZATION TO THE INNER EAR
Osteopontin (OPN) is considered to be a non-collagenous bone matrix protein which is involved in the ossification process. However, OPN has recently been observed in ectopic sites such as the kidneyExpand
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