T. Takano

Publications145
h-index27
Citations2,515
Highly Influential Citations77
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BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of patients.
TLDR
There is no evidence that BRAF(V600E) mutation significantly reflects the aggressive characteristics and poor prognosis of patients with papillary carcinoma in Japan.
Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome.
TLDR
Autoantibodies to CHRM1 were detected in a large number of CFS patients and were related to CFS symptoms, suggesting that subgroups of C FS are associated with autoimmune abnormalities of CHRM 1.
Antitumor effects of peroxisome proliferator activate receptor gamma ligands on anaplastic thyroid carcinoma.
TLDR
The results indicated that PPARgamma ligands modify malignant potential of anaplastic carcinoma cell lines altering growth or invasive properties, suggesting that PPargamma could be potentially the novel molecular target for human thyroid anaplastics carcinoma.
High-throughput differential screening of mRNAs by serial analysis of gene expression: decreased expression of trefoil factor 3 mRNA in thyroid follicular carcinomas
TLDR
Results indicate that the decreased expression of TFF3 mRNA is a marker of follicular carcinomas, especially in widely invasive types and those with evident metastases, especially those with a high risk of invasion or metastasis.
Autoantibodies against four kinds of neurotransmitter receptors in psychiatric disorders
Serum concentrations of dehydroepiandrosterone and dehydroepiandrosterone sulfate and their relation to cytokine production during and after normal pregnancy.
Fetal cell carcinogenesis of the thyroid: theory and practice.
  • T. Takano
  • Medicine, Biology
    Seminars in cancer biology
  • 1 June 2007
No increase of blocking type anti-thyrotropin receptor antibodies during pregnancy in patients with Graves' disease.
TLDR
It is found that activities of TSH-binding inhibitory Igs, TSAb, and TSBAb decrease during pregnancy and increase after delivery, suggesting that amelioration of Graves' disease during pregnancy is induced by decrease of TSAb but not by the appearance of TSBAB.
Decreased relative expression level of trefoil factor 3 mRNA to galectin-3 mRNA distinguishes thyroid follicular carcinoma from adenoma.
Natural history of thyroid cancer [Review].
  • T. Takano
  • Medicine, Biology
    Endocrine journal
  • 2 February 2017
TLDR
Findings strongly suggested the existence of self-limiting cancers, which are truly malignant but do not progress to lethal cancers, for the first time in human history.
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