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Comparison of anticonvulsive and acute neuroprotective activity of three 2,3-benzodiazepine compounds, GYKI 52466, GYKI 53405, and GYKI 53655
GYKI 52466 [1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine], a non-competitive AMPA [alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate] and kainate receptor antagonist and itsExpand
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Electrical Forepaw Stimulation During Reversible Forebrain Ischemia Decreases Infarct Volume
Background and Purpose— Functional stimulation is accompanied by increases in regional cerebral blood flow which exceed metabolic demands under normal circumstances, but it is unknown whetherExpand
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An exponential functional of random walks
The aim of this paper is to investigate discrete approximations of the exponential functional of Brownian motion (which plays an important role in Asian options of financial mathematics) with theExpand
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An elementary introduction to the Wiener process and stochastic integrals
An elementary construction of the Wiener process is discussed, based on a proper sequence of simple symmetric random walks that uniformly converge on bounded intervals, with probability 1. ThisExpand
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A chronic Alzheimer’s model evoked by mitochondrial poison sodium azide for pharmacological investigations
Alzheimer's disease (AD) is a neurodegenerative disorder and accounts for 50-70% of all dementia cases affecting more than 12 million people worldwide. The primary cause of the disease is presentlyExpand
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T Cells Survey the Stability of the Self: A Testable Hypothesis on the Homeostatic Role of TCR-MHC Interactions
In the lifetime of an individual, every single gene will have undergone mutation on about 1010 separate occasions. Nevertheless, cancer occurs mainly with advancing age. Here, we hypothesize that theExpand
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A new homeostatic model of the T cell system
Our main tenet argues that the primary role of positive thymic selection and the resulting T cell population is the maintenance of a homeostatic equilibrium with self MHC-self peptide complexes. TheExpand
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Stochastic Integration Based on Simple, Symmetric Random Walks
Abstract A new approach to stochastic integration is described, which is based on an a.s. pathwise approximation of the integrator by simple, symmetric random walks. Hopefully, this method isExpand
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An elementary approach to Brownian local time based on simple, symmetric random walks
TLDR
We define Brownian local time as the almost sure limit of the local times of a nested sequence of simple, symmetric random walks. Expand
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