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The role of mu- and kappa-opioid receptors in cocaine-induced conditioned place preference.
- T. Suzuki, Y. Shiozaki, Y. Masukawa, M. Misawa, H. Nagase
- Biology, PsychologyJapanese journal of pharmacology
Results suggest that mu- and kappa-opioid receptors may be involved in cocaine-induced conditioned place preference and that the antagonism of cocaine- induced place preference by U-50,488H or naltrexone does not result from a functional antagonism.
Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase
It is demonstrated that HA1077 is a novel type of arterial vasodilator that had little effect on cyclic nucleotide phosphodiesterases, yet it potently inhibited protein kinases such as cyclicucleotide dependent protein kinase and Ca2+/calmodulin dependent myosin light chain kinase.
Mecamylamine-precipitated nicotine-withdrawal aversion in rats.
Antinociceptive effects of the selective non-peptidic delta-opioid receptor agonist TAN-67 in diabetic mice.
Blockade of morphine reward through the activation of kappa-opioid receptors in mice.
The effects of systemic (s.c.) treatment with the kappa-agonists U-50,488H and E-2078 (a stable dynorphin analog) on the morphine-induced place preference were examined in mice, implying that activation of the mesolimbic DA system may play an important role in the morphine's place preference in mice.
Different roles of mu-, delta- and kappa-opioid receptors in ethanol-associated place preference in rats exposed to conditioned fear stress.
The results suggest that mu- and delta-opioid receptors may play critical roles in the rewarding mechanism of ethanol, and that kappa-operative receptors may modulate the development of the rewarding effect of ethanol under psychological stress.
Involvement of the opioid system in the anxiolytic effect of diazepam in mice.
Implication of brain-derived neurotrophic factor in the release of dopamine and dopamine-related behaviors induced by methamphetamine
Activation of ventral tegmental GABAB receptors inhibits morphine-induced place preference in rats.