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Acute exacerbation of interstitial pneumonia associated with collagen vascular diseases
TLDR
It is suggested that AE can occur in CVD-IP, and this condition is closely similar to that of IPF with poor prognosis. Expand
Interstitial lung diseases associated with amyopathic dermatomyositis
TLDR
The aim of the present study was to clarify the clinical characteristics and prognosis of patients with interstitial lung disease (ILD) associated with amyopathic dermatomyositis (ILD-ADM), which includes two different forms, the acute and chronic forms, with distinct prognoses. Expand
Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages.
TLDR
Data indicate that PPARgamma expressed by AMs play an antiinflammatory role through inhibiting cytokine production and increasing their CD36 expression together with the enhanced phagocytosis of apoptotic neutrophils, which is an essential process for the resolution of inflammation. Expand
Mouse lung CD103+ and CD11bhigh dendritic cells preferentially induce distinct CD4+ T-cell responses.
TLDR
The data suggest that mouse CD103(+) LDCs predominantly elicit Th1 and Th17 responses, whereas CD11b(high) L DCs primarily provoke a Th2 response under the steady state. Expand
The Multicenter Study of a New Assay for Simultaneous Detection of Multiple Anti-Aminoacyl-tRNA Synthetases in Myositis and Interstitial Pneumonia
TLDR
An enzyme-linked immunosorbent assay (ELISA) system using a mixture of recombinant ARS antigens and tested its utility in a multicenter study will enable easier and wider use in the detection of anti-ARS antibodies in patients with IIM and IIP. Expand
Differences in clinical features and prognosis of interstitial lung diseases between polymyositis and dermatomyositis.
TLDR
DM-ILD is more refractory to corticosteroid therapy, resulting in poorer prognosis compared with PM-ILD, and data indicate that intensive therapy, including cyclosporine, should be considered for DM-ILD. Expand
Higher sensitivity and specificity for diffusion-weighted imaging of malignant lung lesions without apparent diffusion coefficient quantification.
TLDR
LSR measurement on high-b value DW imaging may be useful for differentiating between benign and malignant lung nodules, while there were no significant differences between them in relation to ADC. Expand
Alterations in smoking habits are associated with acute eosinophilic pneumonia.
TLDR
Data suggest that recent alterations in smoking habits, not only beginning to smoke, but also restarting to smoke and increasing daily smoking doses, are associated with the development of AEP. Expand
Acute exacerbation in rheumatoid arthritis-associated interstitial lung disease: a retrospective case control study
TLDR
In patients with RA-ILD, older age at ILD diagnosis, UIP pattern on HRCT and methotrexate usage are associated with the development of AE, and AE has a serious impact on their survival. Expand
Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer
TLDR
It is concluded that an increase in PD-L 1 gene copy number can be a feasible alternative biomarker for predicting response to anti-PD-1/PD-L1 therapy. Expand
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