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Dry powder inhalers: the influence of device resistance and powder formulation on drug and lactose deposition in vitro.
TLDR
Measurement of the pressure drop across the devices investigated in this study showed that the two types of Inhalator Ingelheim had the highest resistance, whilst lower pressure drops were found across the Diskhaler, Cyclohaler and Accuhaler devices. Expand
The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production
TLDR
It is found that SS produced from various extraction methods has different molecular weights, zeta potential, particle size and amino acid content, and SS from all extraction methods could still promote collagen production in a concentration-dependent manner, even at high concentrations that are toxic to cells. Expand
Potential applications of silk sericin, a natural protein from textile industry by-products
TLDR
Fibroin has been used in textile manufacturing and for several biomaterial applications, whereas sericin is considered a waste material in the textile industry; however, after mixing with other polymers and cross-linking it can form a film or a scaffold with good characteristics that can be used in the cosmetic and pharmaceutical industries. Expand
Isoniazid Proliposome Powders for Inhalation—Preparation, Characterization and Cell Culture Studies
TLDR
INH-proliposomes were evidently nontoxic to respiratory-associated cells, and did not activate AM to produce inflammatory mediators—including interleukin-1β, tumor necrosis factor-α (TNF-α), and nitric oxide—at a toxic level, and are potential candidates for an alternative tuberculosis treatment. Expand
Formulation and characterization of silk sericin-PVA scaffold crosslinked with genipin.
TLDR
The results indicated that the composition of the scaffolds had a significant effect on their physical properties, and that can easily be tuned to obtain scaffolds suitable for biological applications. Expand
Evaluation of the wound healing potential of Wedelia trilobata (L.) leaves.
TLDR
The scientific findings of wound healing activity supports the traditional claims for Wedelia trilobata (L.) leaves, however further studies to isolate the antibacterial, antioxidant and fibroblast stimulatory compounds that contribute to the wound healing properties of this plant are needed. Expand
Properties and antityrosinase activity of sericin from various extraction methods
TLDR
Pigments, primarily flavonoids and carotenoids from silk cocoons, were found to enhance tyrosinase inhibition of SS and urea extraction was the only method that provided clearly distinguishable bands and had the most significant impact on SS conformation. Expand
In vitro probiotic properties of Lactobacillus fermentum SK5 isolated from vagina of a healthy woman.
TLDR
It is likely that this lactobacillus strain isolated from a vaginal tract of a healthy woman could be a potential probiotic candidate for beneficial use in protecting against gastrointestinal and vaginal microbial infections. Expand
Inhaled pyrazinamide proliposome for targeting alveolar macrophages
TLDR
PZA-proliposomes were less toxic to respiratory-associated cells, and did not activate AMs to produce inflammatory mediators, including interleukin-1β, tumor necrosis factor-α, and nitric oxide, at a toxic level, suggesting that PZA- Proliposome are potential candidates for pulmonary tuberculosis treatment. Expand
Wound healing activity of ent-kaura-9(11),16-dien-19-oic acid isolated from Wedelia trilobata (L.) leaves.
TLDR
The present study provides some scientific evidence for the traditional use of W. trilobata in the management of wound healing due to a combination of antimicrobial, stimulation of fibroblast growth and protection of the cells from hydrogen peroxide-induced injury, all of which could play some role in its effect on tissue repair. Expand
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