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Treatment of Knee Joint Osteoarthritis with Autologous Platelet-Rich Plasma in Comparison with Hyaluronic Acid
TLDR
The preliminary findings support the application of autologous PRP as an effective and safe method in the treatment of the initial stages of knee osteoarthritis.
Limited genetic diversity of Aerococcus viridans strains isolated from clinical and subclinical cases of bovine mastitis in Slovakia.
TLDR
The Aerococcus viridans isolates from bovine mastitis in Slovakia were isolated and characterized by classical microbiological and biochemical, and molecular techniques including IGS-PCR and rep- PCR, ARDRA and 16S rDNA gene sequencing, and the data obtained suggest that a few A.viridans strains spread among cow's population in Slovak farms.
Mesenchymal Stem Cells in the Treatment of Type 1 Diabetes Mellitus
TLDR
This review presents and discusses new approaches of using MSCs in the treatment of diabetes mellitus type 1 and shows that these cells may use pro-angiogenic and immunomodulatory effects to control diabetes following the cotransplantation with pancreatic islets.
Modulation properties of factors released by bone marrow stromal cells on activated microglia: an in vitro study
TLDR
A new non-cell based (cell-free) therapeutic approach applied to BV2 microglial cells and spinal cord derived primary microglia using conditioned media from rat bone marrow stromal cells is developed, confirming the anti-migratory and NO-inhibitory effects of BMSCs-CM on SCI-CM-activatedmicroglia with higher impact on primary microGlia.
Influence of Kartogenin on Chondrogenic Differentiation of Human Bone Marrow-Derived MSCs in 2D Culture and in Co-Cultivation with OA Osteochondral Explant
TLDR
The preliminary results support the concept that 10 µM KGN enhances proliferation and chondrogenic differentiation of hBMSCs and suggest that KGN is a potential promoter for cell-based therapeutic application for cartilage regeneration.
New therapeutic approaches of mesenchymal stem cells-derived exosomes
TLDR
The therapeutic potential of MSC-derived exosomes in experimental models and recent clinical trials to evaluate their safety and efficacy are summarized in this study.
Effect of PRP and PPP on proliferation and migration of human chondrocytes and synoviocytes in vitro
TLDR
Results demonstrate that directed cell proliferation and migration are inducible in human articular CCs and SCs, and that both platelet-derived fractions may exert a positive effect and modulate several cell responses that are potentially involved in tissue integration during cartilage repair.
Isolation, cultivation and characterisation of pigeon osteoblasts seeded on xenogeneic demineralised cancellous bone scaffold for bone grafting
TLDR
The preliminary in vitro results indicate that demineralised cancellous bone from ostrich tibia could provide an effective biological support for growth and proliferation of allogeneic osteoblasts derived from cancellousBone of pigeons.
Two Rep Genes in Small Cryptic Plasmid pKST21 of Escherichia coli
TLDR
Plasmid pKST21 possesses two conversely oriented open reading frames encoding proteins with a high degree of amino acid identity to Rep proteins involved in replication, which indicates a mosaic structure of the plasmid with different segments acquired from different sources.
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