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Expression of an alpha cardiac-like myosin heavy chain in muscle spindle fibres
It is shown that a myosin heavy chain isoform hitherto unknown for skeletal muscle is specifically expressed in rat nuclear bag fibres and that motor innervation influences the expression of this isomyosin along the length of the fibres. Expand
Fibre type composition of soleus and extensor digitorum longus muscles in normal female inbred Lewis rats.
The content of slow fibres in the soleus muscle of female inbred Lewis rats was slightly higher than that reported for Wistar rats, but was considerably higher than those of Sprague-Dawley rats, whereas substantial differences were not found in the proportion of slow and fast fibre types in EDL muscles in these strains. Expand
Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments
- J. Čmielová, R. Havelek, +10 authors M. Řezáčová
- Biology, Medicine
- International journal of radiation biology
- 21 February 2012
Mesenchymal stem cells isolated from bone marrow and periodontal ligament respond to ionizing radiation by induction of stress-induced premature senescence without apparent differences in their radiation response. Expand
Demonstration of myosin heavy chain isoforms in rat and humans: the specificity of seven available monoclonal antibodies used in immunohistochemical and immunoblotting methods.
The results imply that the reactivity of antibodies specific to distinct MyHC isoforms should be carefully evaluated not only among various species but with the two different techniques used as well. Expand
Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis.
- D. Muthná, T. Soukup, +9 authors M. Řezáčová
- Biology, Medicine
- Stem cells and development
- 23 March 2010
It is concluded that DPSCs respond to IR-induced damage by permanent cell cycle arrest in the G2 phase and by stress-induced premature senescence. Expand
The development of Golgi tendon organs
The Ib sensory axon together with Schwann cells appear to be the main formative agents in the GTO development, the Ib terminals presumably inducing the retraction of myotubes from the aponeurosis, and the Schwann Cells affecting the assembly of collagen fibrils and bundles surrounding the terminals. Expand
Human Dental Pulp Stem Cells - Isolation and Long Term Cultivation.
The results of the experiments proved that the DPSCs and MPCs are highly proliferative, clonogenic cells that can be expanded beyond Hayflick's limit and remain cytogenetically stable. Expand
Characterization of Dental Pulp Stem Cells from Impacted Third Molars Cultured in Low Serum-Containing Medium
- J. Karbanová, T. Soukup, J. Suchánek, R. Pytlík, D. Corbeil, J. Mokrỳ
- Medicine, Chemistry
- Cells Tissues Organs
- 11 November 2010
The data show that DPSCs are self-renewing and able to express markers of bone, cartilage, vascular and neural tissues, suggesting their multipotential capacity. Expand
Disease Activity Composite Indices in Patients with Rheumatoid Arthritis and Concomitant Fibromyalgia
The ambiguous results of this study showed that patients with RAF had significantly higher disease activity measured by the 28-joint Disease Activity Score (DAS-28) but significantly more severe joint destruction was revealed in patients with RA. Expand
Dental pulp stem cells and their characterization.
- J. Suchánek, T. Soukup, B. Visek, R. Ivančaková, L. Kučerová, J. Mokrỳ
- Biology, Medicine
- Biomedical papers of the Medical Faculty of the…
- 1 March 2009
It was shown that ITS supplement in the cultivation media greatly increased the proliferative activity of DPSCs and other DPSC biological properties and phenotype were not affected. Expand