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Invited review: reliability of genomic predictions for North American Holstein bulls.
Genetic progress will increase when breeders examine genotypes in addition to pedigrees and phenotypes. Genotypes for 38,416 markers and August 2003 genetic evaluations for 3,576 Holstein bulls born… Expand
Development and Characterization of a High Density SNP Genotyping Assay for Cattle
The success of genome-wide association (GWA) studies for the detection of sequence variation affecting complex traits in human has spurred interest in the use of large-scale high-density single… Expand
A whole-genome assembly of the domestic cow, Bos taurus
BackgroundThe genome of the domestic cow, Bos taurus, was sequenced using a mixture of hierarchical and whole-genome shotgun sequencing methods.ResultsWe have assembled the 35 million sequence reads… Expand
A second-generation linkage map of the bovine genome.
We report a bovine linkage map constructed with 1236 polymorphic DNA markers and 14 erythrocyte antigens and serum proteins. The 2990-cM map consists of a sex-specific, X chromosome linkage group and… Expand
SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries
High-density single-nucleotide polymorphism (SNP) arrays have revolutionized the ability of genome-wide association studies to detect genomic regions harboring sequence variants that affect complex… Expand
Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle
The domestication and development of cattle has considerably impacted human societies, but the histories of cattle breeds and populations have been poorly understood especially for African, Asian,… Expand
Analysis of copy number variations among diverse cattle breeds.
Genomic structural variation is an important and abundant source of genetic and phenotypic variation. Here, we describe the first systematic and genome-wide analysis of copy number variations (CNVs)… Expand
Detection of quantitative trait loci affecting milk production, health, and reproductive traits in Holstein cattle.
We report putative quantitative trait loci affecting female fertility and milk production traits using the merged data from two research groups that conducted independent genome scans in Dairy Bull… Expand
Copy number variation of individual cattle genomes using next-generation sequencing.
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in or near segmental duplication regions are often intractable. Using a read depth approach based on… Expand
Genomic characteristics of cattle copy number variations
BackgroundCopy number variation (CNV) represents another important source of genetic variation complementary to single nucleotide polymorphism (SNP). High-density SNP array data have been routinely… Expand