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An 8-year follow-up of 450 sons of alcoholic and control subjects.
BACKGROUND Between 1978 and 1988, 453 sons (age range, 18-29 years) of alcoholic and control subject were evaluated for their level of reaction (LR) to alcohol. This article presents the results ofExpand
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TEMPS-A: validation of a short version of a self-rated instrument designed to measure variations in temperament.
OBJECTIVE To validate a short English-language version of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A), a self-report questionnaire designed toExpand
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An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk.
BACKGROUND Alcoholism is a complex, genetically influenced disorder the cause of which may be better understood through the study of genetically influenced phenotypes that mediate the risk. One suchExpand
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Effect of Patient Activation on Self-Management in Patients With Heart Failure
Background/Objective:Few studies have examined whether chronic heart failure (HF) outcomes can be improved by increasing patient engagement (known as activation) in care and capabilities forExpand
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The sleep of abstinent pure primary alcoholic patients: natural course and relationship to relapse.
Sleep in male pure primary alcoholic inpatients was examined at a mean of 16 days (n = 29), 19 weeks (n = 29), 14 months (n = 9), and 27 months (n = 4) of abstinence. Results were as follows: (1) theExpand
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Development and validation of a Rasch-derived CES-D short form.
The current study presents a Rasch-derived short form of the Center for Epidemiologic Studies-Depression scale (CES-D) for use as a depression screening tool in the general population. In contrast toExpand
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Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABAα6 receptors and the serotonin transporter in the level of response to alcohol: a pilot study
BACKGROUND The vulnerability to alcohol dependence appears to be genetically influenced through a variety of mechanisms. One potentially genetically mediated channel may be a low level of responseExpand
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The Self-Rating of the Effects of alcohol (SRE) form as a retrospective measure of the risk for alcoholism.
AIMS A low level of response (LR) to alcohol is a characteristic of sons of alcoholics and predicts an elevated future alcoholism risk. A 12-question Self-Rating of the Effects (SRE) of alcohol formExpand
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The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders.
OBJECTIVE Numerous biological and sociocultural factors have been proposed as potentially important to the risk for alcohol use disorders. This study evaluates the relationships to alcohol abuse orExpand
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Comparison of 3190 alcohol-dependent individuals with and without suicide attempts.
INTRODUCTION Suicidal behaviors are often seen in alcohol-dependent individuals. The aim of this study is to identify and confirm risk factors for suicide attempts in a large, family-based sample ofExpand
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