T. Simon

Publications144
h-index39
Citations5,043
Highly Influential Citations225
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • S. Eliez
  • 291 Publications, 12,293 Citations
  • W. Kates
  • 131 Publications, 5,452 Citations
  • C. Bearden
  • 393 Publications, 15,357 Citations
  • B. Emanuel
  • 425 Publications, 22,422 Citations
  • Publications
  • Influence
Volumetric, connective, and morphologic changes in the brains of children with chromosome 22q11.2 deletion syndrome: an integrative study
TLDR
Chromosome 22q11.2 deletion syndrome is a highly prevalent genetic disorder whose manifestations include developmental disability and sometimes mental retardation. Expand
  • 197
  • 30
  • PDF
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
Recent studies are beginning to paint a clear and consistent picture of the impairments in psychological and cognitive competencies that are associated with microdeletions in chromosome 22q11.2.… Expand
  • 393
  • 20
  • PDF
Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.
OBJECTIVE Chromosome 22q11.2 deletion syndrome is a neurogenetic disorder associated with high rates of schizophrenia and other psychiatric conditions. The authors report what is to their knowledge… Expand
  • 444
  • 14
Programmable user models for predictive evaluation of interface designs
TLDR
A Programmable User Model (PUM) is a psychologically constrained architecture which an interface designer is invited to program to simulate a user performing a range of tasks with a proposed interface, by involving the designer in the process of making predictions of usability. Expand
  • 178
  • 10
Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome.
OBJECTIVE The 22q11.2 deletion syndrome (DiGeorge/velocardiofacial syndrome) is associated with attentional problems and executive dysfunction, and is one of the highest known risk factors for… Expand
  • 123
  • 8
  • PDF
Structure-specific statistical mapping of white matter tracts
TLDR
This paper describes a new statistical analysis framework for diffusion-based white matter studies. Expand
  • 175
  • 7
  • PDF
A new account of the neurocognitive foundations of impairments in space, time and number processing in children with chromosome 22q11.2 deletion syndrome.
  • T. Simon
  • Psychology, Medicine
  • Developmental disabilities research reviews
  • 2008
In this article, I present an updated account that attempts to explain, in cognitive processing and neural terms, the nonverbal intellectual impairments experienced by most children with deletions of… Expand
  • 84
  • 7
  • PDF
Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study.
CONTEXT Precocious amygdala enlargement is commonly observed in young children with autism. However, the age at which abnormal amygdala enlargement begins and the relative growth trajectories of the… Expand
  • 136
  • 6
  • PDF
Atypical cortical connectivity and visuospatial cognitive impairments are related in children with chromosome 22q11.2 deletion syndrome
BackgroundChromosome 22q11.2 deletion syndrome is one of the most common genetic causes of cognitive impairment and developmental disability yet little is known about the neural bases of those… Expand
  • 60
  • 6
  • PDF
White matter microstructural abnormalities in girls with chromosome 22q11.2 deletion syndrome, Fragile X or Turner syndrome as evidenced by diffusion tensor imaging
TLDR
We scanned 101 female children between 7 and 14years old: 25 with 22q11.2DS, 18 with FXS, 17 with TS, and 41 aged-matched controls using diffusion tensor imaging (DTI). Expand
  • 51
  • 6
  • PDF