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Lecithinized superoxide dismutase retards wobbler mouse motoneuron disease
Gene mutations of Cu/Zn superoxide dismutase (SOD) have been discovered in familial amyotrophic lateral sclerosis (ALS). Oxidative stress also plays a role in the pathogenesis of sporadic ALS.Expand
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Increased plasma concentrations of aspartate, glutamate and glycine in Parkinson's disease
We measured fasting plasma amino acids in 20 patients with Parkinson's disease (PD) and 20 controls matched for age and sex. PD patients had significant elevations in plasma levels of aspartate,Expand
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Concurrence of myasthenia gravis and chorée fibrillaire de morvan
SummaryA case of myasthenia gravis associated with a syndrome resembling “chorée fibrillaire de Morvan” is described. This association has not been previously noted in the literature. It isExpand
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Catalytic Cracking of Naphtha to Light Olefins
A catalytic process that produces light olefins from naphtha was developed to improve the yield of the conventional steam cracker. In laboratory-scale tests, a newly developed zeolite-based catalystExpand
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Neuroprotective effect of various cytokines on developing spinal motoneurons following axotomy
Ciliary neurotrophic factor (CNTF), a multipoietic factor, on a variety of neurons, prevents axotomy-induced motoneuron loss and can improve the outcome of murine motor neuron disease (MND). WeExpand
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Coadministration of interleukin-6 (IL-6) and soluble IL-6 receptor delays progression of wobbler mouse motor neuron disease
Interleukin-6 (IL-6), a multipotential cytokine, initiates signal transduction pathways similar to those of ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF). These moleculesExpand
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Cognitive impairment in amyotrophic lateral sclerosis and its relation to motor disabilities
The performance of patients with amyotrophic lateral sclerosis (ALS) on selective neuropsychological tests was examined in regard to the applicability of such examinations to diagnosis. EighteenExpand
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Neuropsychological dysfunctions in amyotrophic lateral sclerosis: relation to motor disabilities.
A study was undertaken to elucidate the existence of cognitive and memory impairments in patients with amyotrophic lateral sclerosis (ALS) by comparing a group of ALS patients with bothExpand
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Deprenyl and pergolide rescue spinal motor neurons from axotomy-induced neuronal death in the neonatal rat.
It has been reported that both the monoamine oxidase inhibitor, deprenyl and the dopamine receptor agonist, pergolide have neuroprotective actions. To investigate the effect of deprenyl and pergolideExpand
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