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Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.
Because the aberrantly activated phosphoinositide 3-kinase (PI3K)/Akt pathway renders tumor cells resistant to cytotoxic insults, including those related to anticancer drugs, inhibition of theExpand
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Supratentorial primitive neuroectodermal tumor in an aged patient--case report--.
An 88-year-old woman presented with a supratentorial primitive neuroectodermal tumor (PNET) manifesting as disturbance of consciousness and left hemiplegia. Magnetic resonance imaging showed a largeExpand
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A new, miniature ultrasonic surgical aspirator with a handpiece designed for transsphenoidal surgery. Technical note.
The authors describe an innovative surgical instrument designed to remove hard fibrous masses from the pituitary region, which cannot be completely removed using standard transsphenoidal surgicalExpand
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Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor.
OBJECT The phosphatase and tensin homolog deleted from chromosome 10 (PTEN) functions as a tumor suppressor by negatively regulating the growth/survival signals of the phosphatidylinositol 3-kinaseExpand
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[Primary oculomotor nerve palsy due to head injury: analysis of 10 cases].
Ten cases of primary oculomotor nerve palsy due to head injury are presented. All ten patients had a dilated, non reactive pupil. Seven had complete oculomotor palsy. Two had partial extraocularExpand
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Experimental validation of deuterium oxide-mediated antitumoral activity as it relates to apoptosis in murine malignant astrocytoma cells.
OBJECT Deuterium oxide (D2O), or heavy water, affects a variety of biological activities different from those of water. The authors examined the antitumoral effect of D2O on brain neoplasms andExpand
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[A case of deep sylvian meningioma presenting temporal lobe epilepsy].
A rare case of deep sylvian meningioma is presented. A 62-year-old woman was admitted to our hospital because of one year history of temporal lobe epilepsy. She had no neurological deficit except forExpand
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Meningioma with hypergammaglobulinemia. Case report.
The case of a 14-year-old boy presenting with hypergammaglobulinemia (immunoglobulin (Ig)G and IgA) and a cerebellopontine angle tumor is reported. The tumor was histologically confirmed asExpand
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Spontaneous subperiosteal hematoma of the orbit--case report.
A 62-year-old female was admitted with complaints of sudden proptosis of the left eye and severe left orbital pain without history of trauma or previous illness. Computed tomography and magneticExpand
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[Regional continuous intraarterial infusion of urokinase in the acute stage of cervical and intracranial major artery occlusion--particularly on a case of successful improvement after therapeutic
We recently applied regional continuous intraarterial infusion of urokinase (UK) for five cases suffering from occlusion of the cervical and intracranial major arteries within nine hours from theExpand
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