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Catalog of Teratogenic Agents
The ninth edition of this reference for teratogenic agents, emphasizes human data and covers pharmaceuticals, chemicals, environmental pollutants, food additives, household products and viruses.…
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National toxicology program.
  • T. Shepard
  • Environmental Science
    Teratology
  • 1 February 1981
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Brain growth in Down syndrome subjects 15 to 22 weeks of gestational age and birth to 60 months.
TLDR
It is suggested that the prenatal retardation of neurogenesis begins after 22 weeks' gestational age, and the postnatal retardedation of brain growth is secondary to pre- and postnatal abnormalities in synaptogenesis.
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Human growth hormone
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Familial Addison's disease; case reports of two sisters with corticoid deficiency unassociated with hypoaldosteronism.
TLDR
The Addisonian-like aspect of the familial disease, congenital adrenal hyperplasia, has been reviewed and the syndrome is reported as occurring in two sisters and in two brothers because of pigmentation and decreased serum sodium.
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Aspirin and acetaminophen use by pregnant women and subsequent child IQ and attention decrements.
TLDR
Aspirin effects on offspring function were found in the absence of effects on physical size both at birth and at 4 years, and continuous dose-response and step-function parameterizations of aspirin exposure were both statistically significant and not clearly distinguishable from each other.
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Glucose absorption and utilization by rat embryos.
TLDR
A role of this microvillar elongation in degenerative changes seen in uncontrolled diabetes and on function of the immune system is proposed.
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A selection of candidate compounds for in vitro teratogenesis test validation.
TLDR
This communication established a list of 47 compounds or conditions which demonstrate a wide range of teratogenicity in vivo, intended to serve as a base for in vitro teratogenesis test validation and should prove useful in developing and identifying those systems which will contribute to a more effective testing program.
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Dehydroepiandrosterone and androsterone levels in human plasma: effect of age and sex; day-to-day and diurnal variations.
TLDR
The present study was carried out to obtain further information on the levels of DHA and androsterone in normal subjects and to ascertain the effect of age and sex on the concentrations of these steroids.
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Histochemical studies of the human fetal thyroid during the first half of fetal life
TLDR
A number of histologic and histochemical techniques have been used to study 42 human fetal thyroids from fresh specimens ranging in crown‐rump length from 22 to 201 mm and found no change in the average cell height was found during differentiation.
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