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Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation
TLDR
This work investigated whether ENV protein affects oligodendroglial differentiation and found that it can mediate injury to specific cell types of the brain and immune system. Expand
The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade
TLDR
Beyond immune cell modulation, this monoclonal antibody may therefore help to overcome the oligodendroglial differentiation blockade in MS. Expand
Non-epileptic seizures in autonomic dysfunction as the initial symptom of COVID-19
TLDR
This case is described the first case of COVID-19 that initially exhibited non-epileptic seizures (convulsive syncope) in autonomic dysfunction and SARS-CoV-2-RNA could not be found in the CSF using an RT-PCR assay. Expand
ACTRIMS-ECTRIMS MSBoston 2014: Late Breaking News Poster Session
TLDR
A strong positive association is reported between testicular hypofunction (TH), as a proxy for low testosterone levels, and subsequent MS in males, and obesity is unlikely to be an important confounder. Expand
The role of the MSRV envelope protein on oligodendroglial differentiation in the context of demyelinating diseases of the central nervous system
Oligodendrozyten produzieren die Myelinscheiden, welche zur Isolierung neuronaler Axone im zentralen Nervensystem (ZNS) notwendig sind. Eine intakte Myelinscheide ermoglicht eine beschleunigteExpand