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Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts.
TLDR
Results may have implications for the NER process in vivo in that coordinately occurring dual incisions by XPG and XPF/ERCC1 proteins play an important role in inducing PCNA complex formation, but the step may not be required for PCNA-dependent repair of X-ray-induced DNA damage.
Dynamic changes in subnuclear NP95 location during the cell cycle and its spatial relationship with DNA replication foci.
TLDR
The results indicate that NP95 is assigned to a late growth-regulated gene and suggest thatNP95 does not take a direct part in DNA replication as part of the DNA synthesizing machinery, but is presumably involved in other DNA replication-linked nuclear events.
Two types of proliferating cell nuclear antigen (PCNA) complex formation in quiescent normal and xeroderma pigmentosum group A fibroblasts following ultraviolet light (uv) irradiation.
TLDR
The results suggest that there exist two types of PCNA complex formation, nucleotide excision repair-related and -unrelated, in human fibroblasts following uv irradiation.
Effect of IL-12 encoding plasmid administration on tight-skin mouse.
TLDR
Results indicate that pCAGGSIL-12 administration into Tsk/+ mice had beneficial effects in preventing the collagen accumulation in the skin and suppressing the autoimmunity via improvement of Th1/Th2 balance.
Induction of proliferating cell nuclear antigen (PCNA) complex formation in quiescent fibroblasts from a xeroderma pigmentosum patient
TLDR
It was concluded that PCNA complex formation was commonly induced in at least three conditions to produce UDS in spite of different types of DNA damages and DNA repair mechanisms.
Roles of CD4+ and CD8+ cells, and the effect of administration of recombinant murine interferon gamma in listerial infection
TLDR
Findings indicated that CD8+ cells were responsible for causing irreversible systemic Listeria infection and severe liver necrosis.
CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver
TLDR
CD10 expression in CRC cells abrogates the anti-tumour effect of hepatic MENK by degrading it, which enhances liver metastasis of CD10-positive CRC cells.
Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after gamma-irradiation.
TLDR
It is indicated that apoptotic activity does not necessarily predict clonogenic survival after exposure to ionizing radiation, and clinical implications in the evaluation of apoptotic activities observed during the course of radiotherapy to predict accurate tumor response or local control are provided.
Role of glutathione in the intrinsic radioresistance of cell lines from a mouse squamous cell carcinoma.
TLDR
The results suggest that there may exist GSH-related mechanisms in addition to radical scavenging which determine the intrinsic cellular radioresistance under aerobic conditions.
Modulation of dendritic cell development by immunoglobulin G in control subjects and multiple sclerosis patients
TLDR
The possibility that IgG treatment, apart from its known ability to regulate inflammation, may help to prevent relapses of MS by controlling DC maturation is suggested, consequently inhibiting invasion of immune cells into the central nervous system and affecting the cytokine profile.
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