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Apparent diffusion coefficient of human brain tumors at MR imaging.
PURPOSE To determine if apparent diffusion coefficient (ADC) can be used to differentiate brain tumors at magnetic resonance (MR) imaging. MATERIALS AND METHODS Institutional review board approval… Expand
Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud
RETINOIC acid is a putative morphogen in limb formation in the chick and other vertebrates1-5. In chick limb formation, it is thought that retinoic acid is released from the zone of polarizing… Expand
Cytoplasmic, but not nuclear, p16 expression may signal poor prognosis in high-grade astrocytomas
SummaryBackgroundThe negative consequences of the cytoplasmic localization of p16 in patients with high-grade astrocytomas, on their prognosis, was investigated.Methodsp16 Expression was examined in… Expand
Magnetic resonance spectroscopic detection of lactate is predictive of a poor prognosis in patients with diffuse intrinsic pontine glioma.
Diffuse brainstem glioma has a poor prognosis, and there are few long-term survivors. We looked for clinical, conventional magnetic resonance (MR), and MR spectroscopic (MRS) findings predictive of… Expand
Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors.
OBJECT The objective of the present study was to perform a prospective evaluation of the potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin sodium and… Expand
11C-Methionine Uptake Correlates with Combined 1p and 19q Loss of Heterozygosity in Oligodendroglial Tumors
BACKGROUND AND PURPOSE: Oligodendroglial tumors with 1p/19q LOH are known to show longer patient survival than those without 1p/19q LOH, but the reason for this clinical difference has not been… Expand
Intraoperative cortico-cortical evoked potentials for the evaluation of language function during brain tumor resection: initial experience with 13 cases.
OBJECTIVES The objective in the present study was to evaluate the usefulness of cortico-cortical evoked potentials (CCEP) monitoring for the intraoperative assessment of speech function during… Expand
Survivin subcellular localization in high-grade astrocytomas: simultaneous expression in both nucleus and cytoplasm is negative prognostic marker
ObjectiveSubcellularly localized (nuclear and/or cytoplasmic) survivin has various functions, and correlates with prognosis of malignant tumors. However, there have been no reports about the… Expand
Prognosis of cerebellar glioblastomas: correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomas.
BACKGROUND Cerebellar glioblastomas (GBM) are rare tumors whose clinicopathological characteristics are not well understood. PATIENTS AND METHODS Clinico-immunohistochemical findings were… Expand
Intraoperative Functional Mapping and Monitoring during Glioma Surgery.
- T. Saito, Y. Muragaki, T. Maruyama, M. Tamura, Masayuki Nitta, Y. Okada
- Neurologia medico-chirurgica
Glioma surgery represents a significant advance with respect to improving resection rates using new surgical techniques, including intraoperative functional mapping, monitoring, and imaging.… Expand