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Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet.
BACKGROUND There is a need for better standardization of the dermoscopic terminology in assessing pigmented skin lesions. OBJECTIVE The virtual Consensus Net Meeting on Dermoscopy was organized toExpand
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NADPH oxidase 4 contributes to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression.
Generation of reactive oxygen species (ROS) has been implicated in carcinogenic development of melanoma, but the underlying molecular mechanism has not been fully elucidated. We studied theExpand
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Eccrine porocarcinoma: Clinical and pathological studies of 12 cases
Twelve cases of eccrine porocarcinoma have been reported at our facility in the past 10 years. All of them were Japanese; half had lymph node metastases; and one‐third died of this disease. LymphExpand
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Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update
BackgroundIn the previous report of the Prognosis and Statistical Investigation Committee of the Japanese Skin Cancer Society, we tabulated data on patients with malignant melanoma who had beenExpand
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Constitutive activation of the mitogen-activated protein kinase signaling pathway in acral melanomas.
One of the most attractive clinical targets for melanoma is the mitogen-activated protein kinase (MAPK) signaling pathway. In this study, we examined MAPK signaling activation in a total of 28 acralExpand
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Molecular pathogenesis of malignant melanoma: a different perspective from the studies of melanocytic nevus and acral melanoma.
The Clark model for melanoma progression emphasizes a series of histopathological changes beginning from benign melanocytic nevus to melanoma via dysplastic nevus. Several models of the genetic basisExpand
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High frequency of BRAFV600E mutation in acquired nevi and small congenital nevi, but low frequency of mutation in medium-sized congenital nevi.
To investigate whether the frequency of the BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) mutation in melanocytic nevi is associated with sun exposure patterns, we examined 120Expand
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Development of a malignant proliferating trichilemmal cyst in a patient with multiple trichilemmal cysts.
A case of multiple trichilemmal cysts is presented. After trauma, a large tumor developed on one of the cysts. The histologic features of this tumor were similar to those of proliferatingExpand
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Updated statistical data for malignant melanoma in Japan
AbstractBackground. A statistical investigation was conducted of Japanese melanoma patients who had been registered by the Prognosis and Statistical Investigation Committee of the Japanese SkinExpand
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In vivo observation of magnified features of pigmented lesions on volar skin using video macroscope. Usefulness of epiluminescence techniques in clinical diagnosis.
BACKGROUND AND DESIGN In vivo epiluminescence microscopy is now used as a useful noninvasive method for determining clinical diagnosis of pigmented skin lesions. Until now, however, pigmented lesionsExpand
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