• Publications
  • Influence
Use of the Danish Adoption Register for the study of obesity and thinness.
Genome-wide association study identifies 74 loci associated with educational attainment
TLDR
Because educational attainment is measured in large numbers of individuals, it will continue to be useful as a proxy phenotype in efforts to characterize the genetic influences of related phenotypes, including cognition and neuropsychiatric diseases. Expand
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and
  • Leandra Ziad A Zargar Abdul Niveen M Benjamin Cecilia Robe Abarca-Gómez Abdeen Hamid Abu-Rmeileh Acosta-Cazar, Leandra Abarca-Gómez, +1,022 authors M. Ezzati
  • Medicine
  • The Lancet
  • 16 December 2017
TLDR
Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls, and by contrast, the rise in BMI has accelerated in east and south Asia forboth sexes, and southeast Asia for boys. Expand
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants
TLDR
The posterior probability of meeting the target of halting by 2025 the rise in obesity at its 2010 levels, if post-2000 trends continue, is calculated. Expand
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
TLDR
The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries, and the contributions of changes in prevalence versus population growth and ageing to the increase. Expand
Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
TLDR
Across the phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association and the two loci associated with depressive symptoms replicate in an independent depression sample. Expand
Combined associations of prepregnancy body mass index and gestational weight gain with the outcome of pregnancy.
TLDR
Heavier women may benefit from avoiding high and very high GWG, which brings only a slight increase in the risk of growth restriction for the infant, and underweight women may want to avoid low GWG to prevent having a small baby. Expand
The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900
TLDR
The nature of genetic influences on longevity is probably non-additive and environmental influences non-shared, and there is no evidence for an impact of shared (family) environment. Expand
Familial occurrence of inflammatory bowel disease.
TLDR
The 10-fold increase in the familial risk of ulcerative colitis and Crohn's disease strongly suggests that these disorders have a genetic cause. Expand
Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics
TLDR
It is revealed that a combination of early exposures, including delivery mode, maternal pre-pregnancy BMI and antibiotics in infancy, influences the risk of overweight in later childhood, which may potentially be explained by an impact on establishment and diversity of the microbiota. Expand
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