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Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure.
Hemodynamics, plasma norepinephrine, and plasma renin activity were measured at supine rest in 106 patients (83 men and 23 women) with moderate to severe congestive heart failure. During follow-upExpand
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Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan.
To determine the reliability and validity of a patient outcome questionnaire for chronic heart failure, a randomized, double-blind, placebo-controlled, 3-month trial of pimobendan, an investigationalExpand
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Validity of the Minnesota Living with Heart Failure questionnaire as a measure of therapeutic response to enalapril or placebo.
Abstract Patients' perspectives concerning the effects of disease and therapy on their lives have become increasingly important for the assessment of medications in clinical trials. The MinnesotaExpand
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Endothelium‐Dependent Vasodilation Is Attenuated in Patients With Heart Failure
BackgroundEndothelial cells produce a number of substances, collectively termed endothelium derived relaxing factor (EDRF), that promote local relaxation of vascular smooth muscle. Although studiesExpand
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Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure.
BACKGROUND Patients with heart failure have reduced peripheral blood flow at rest, during exercise, and in response to endothelium-dependent vasodilators. Nitric oxide formed from L-arginineExpand
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C-Reactive Protein in Heart Failure: Prognostic Value and the Effect of Valsartan
Background—The role of C-reactive protein (CRP) in heart failure is not well studied. We assessed the prognostic value of CRP in patients randomized in Val-HeFT (Valsartan Heart Failure Trial) andExpand
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Association of coronary artery disease in cardiac transplant recipients with cytomegalovirus infection.
Coronary artery disease (CAD) is now the major limitation to long-term survival after cardiac transplantation. Its etiology remains unclear. The possible role of viral infection in the genesis of CADExpand
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Use of the Living With Heart Failure questionnaire to ascertain patients' perspectives on improvement in quality of life versus risk of drug-induced death.
Treatments for heart failure, such as flosequinan, may have opposite effects on survival and quality of life. The Living With Heart Failure questionnaire was used to examine patients' willingness toExpand
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Autonomic regulation therapy via left or right cervical vagus nerve stimulation in patients with chronic heart failure: results of the ANTHEM-HF trial.
OBJECTIVE ANTHEM-HF evaluated a novel autonomic regulation therapy (ART) via either left or right vagus nerve stimulation (VNS) in patients with heart failure (HF) and reduced ejection fractionExpand
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A conceptual model of quality of life in relation to heart failure.
  • T. Rector
  • Medicine
  • Journal of cardiac failure
  • 1 April 2005
Many clinical trials now incorporate measures ranging from simple assessments of symptoms and physical performance tests to more complex multidimensional questionnaires and batteries of measures toExpand
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