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Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression
TLDR
CHIT1 could be a potentially useful marker for differential diagnosis and prediction of disease progression in ALS and, therefore, seems suitable as a supplemental marker for patient stratification in therapeutic trials. Expand
DeepVOG: Open-source pupil segmentation and gaze estimation in neuroscience using deep learning
TLDR
This work proposes to use a fully convolutional neural network (FCNN) for segmentation of the whole pupil area, trained on 3946 VOG images hand-annotated at the institute, and provides code and pre-trained FCNN model open-source and for free. Expand
Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia
TLDR
The findings agree with the neuroanatomically proposed involvement of the cholinergic BF, particularly the NSP, in PPA syndromes and find a shift from a structural covariance of the BF with left hemispheric cortical areas in healthy aging towards right hemispherical cortical areas of PPA. Expand
Lexical retrieval treatment in primary progressive aphasia: An investigation of treatment duration in a heterogeneous case series
TLDR
The results add to the evidence that daily home practice of Repetition and Reading in the Presence of a Picture over extended periods can increase and maintain retrieval of personally-relevant words in picture naming for some individuals with semantic or nonfluent/agrammatic variant PPA. Expand
[Amyloid positron-emission-tomography with [18 F]-florbetaben in the diagnostic workup of dementia patients].
TLDR
Amyloid-PET is currently no standard procedure in the diagnosis of dementia; however, it can be a helpful additional diagnostic tool when used according to the "Appropriate Use Criteria" and the S3 guidelines on dementia. Expand
The human corticocortical vestibular network
TLDR
The analysis delineated a remarkably stable organization of cortical vestibular connectivity, which might explain why cortical lesions in humans do not lead to persistent Vestibular symptoms and buffer the network and reestablish network integrity quickly in case of injury. Expand
WORD RETRIEVAL IN PRIMARY PROGRESSIVE APHASIA FOLLOWING LANGUAGE THERAPY
IE-Map: A novel in-vivo atlas template of the human inner ear
Brain atlases and templates are core tools in scientific research with increasing importance also in clinical applications. Advances in neuroimaging now allowed us to expand the atlas domain to theExpand
IE-Map: a novel in-vivo atlas and template of the human inner ear
Brain atlases and templates are core tools in scientific research with increasing importance also in clinical applications. Advances in neuroimaging now allowed us to expand the atlas domain to theExpand
Naming treatment in three cases of primary progressive aphasia
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