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Validated HPLC analytical method with programmed wavelength UV detection for simultaneous determination of DRF-4367 and Phenol red in rat in situ intestinal perfusion study.
- T. R. Shantha Kumar, Sonia Chawla, S. K. Nachaegari, S. K. Singh, N. Srinivas
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 1 June 2005
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for… Expand
Bioavailability Enhancement of Poorly Water Soluble and Weakly Acidic New Chemical Entity with 2-Hydroxy Propyl-β-Cyclodextrin: Selection of Meglumine, a Polyhydroxy Base, as a Novel Ternary Component
- S. Basavaraj, V. Sihorkar, +5 authors S. Kumar Singh
- Chemistry, Medicine
- Pharmaceutical development and technology
- 1 January 2006
The purpose of the present study was to investigate the influence of a polyhydroxy base, N-acetyl glucamine (also know as Meglumine), as a ternary component on the complexation of DRF-4367, a poorly… Expand