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Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes.
Publisher Summary This chapter discusses the cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes. Peptide mapping is widely used for the study of sites ofExpand
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Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization.
A complex of structurally related compounds that exhibit in vivo antileukemic activity was isolated from fermentation broths of a new streptomycete. The components of this complex are water solubleExpand
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PD 124,895 and PD 124,966, two new antitumor antibiotics.
The isolation and characterization of the title antibiotics, which are produced by the same Streptomyces sp., is described. The potent antitumor agent, PD 124,895, is an analog of hydroxyelactocinExpand
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Effect of chlorine treatment on infectivity of hepatitis A virus.
This study examined the effect of chlorine treatment on the infectivity of hepatitis A virus (HAV). Prodromal chimpanzee feces, shown to induce hepatitis in marmosets (Saguinus sp.), was clarified,Expand
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Isolation and Structure of a New Antibiotic Related to Rubiflavin A
A novel antibiotic, PD 121,222, was isolated from a complex of pluramycin-like compounds containing mostly kidamycin and neopluramycin. Spectral analyses showed that this compound is theExpand
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PD 114,759 and PD 115,028, novel antitumor antibiotics with phenomenal potency. I. Isolation and characterization.
The isolation of two new antibiotics, PD 114,759 and PD 115,028, exhibiting in vivo antitumor activity at extremely low doses is described. The physico-chemical properties of these sulfur-containingExpand
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Synthesis and characterization of pregabalin lactose conjugate degradation products.
Seven degradation products observed in formulated pregabalin have been characterized. These compounds result from Maillard reactions and Amadori rearrangements. Heating pregabalin in the presence ofExpand
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Effect of Sub‐2‐Micron Particle Size on Peak Efficiency, Capacity, and Resolution in Preparative Liquid Chromatography
Abstract Near and above overload concentrations of seven separate compounds were injected onto three separate C18 columns containing 1.7, 3.5, and 5.0 µm particles to determine “loadability” of theExpand
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Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate.
A series of renin inhibitors containing ester side chains at the P2 subsite are potent inhibitors of primate renin. Derivatives containing the diol isostere (ACDMH) at P1-P1' were the most potentExpand
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